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Simultaneous right-sided nephrectomy with orthotopic liver and kidney transplantation-An alternative method for patients with autosomal dominant polycystic liver and kidney disease.
Felgendreff, Philipp; Tautenhahn, Hans-Michael; Lux, Sascha; Dondorf, Felix; Aschenbach, René; Rauchfuss, Falk; Settmacher, Utz.
Afiliación
  • Felgendreff P; Department of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany. P.Felgendreff@gmail.com.
  • Tautenhahn HM; Research Programme "Else Kröner-Forschungskolleg AntiAge", University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany. P.Felgendreff@gmail.com.
  • Lux S; Department of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
  • Dondorf F; Research Programme "Else Kröner-Forschungskolleg AntiAge", University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
  • Aschenbach R; Department of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
  • Rauchfuss F; Department of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
  • Settmacher U; Department of Radiology, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
Langenbecks Arch Surg ; 406(6): 2107-2115, 2021 Sep.
Article en En | MEDLINE | ID: mdl-34036408
PURPOSE: In patients suffering from autosomal dominant polycystic liver and kidney disease (ADPLKD), combined organ transplantation often poses a technical challenge due to the large volume of both organs. To simplify the transplantation procedure by improving the exposure of anatomical structures, we introduce a novel surgical technique of orthotopic liver and kidney transplantation. METHODS: The modified simultaneous liver and kidney transplantation technique via a right-sided L-incision included three steps: (1) right-sided nephrectomy in the recipient followed by (2) orthotopic liver transplantation in cava replacement technique and (3) the orthotopic kidney transplantation with arterial reconstruction to the right common iliac artery. RESULTS: In total, seven patients with ADPLKD were transplanted by using the modified transplantation technique. The mean operation time was 342.43 min (±68.77). Postoperative patients were treated for 6.28 days (±2.50) in the intensive care unit and were discharged from the surgical ward approximately 28 days (±5.66) after the operation with normal graft function. Complications associated with the use of the modified technique, such as bleeding, anastomotic stenosis, biloma, or urinoma, did not occur. CONCLUSION: Modified simultaneous liver and kidney transplantation is a safe alternative for patients with ADPLKD. By combining right-sided nephrectomy and orthotopic graft transplantation, the approach optimizes the exposure of anatomical structures and simplifies the transplantation procedure. Additionally, the modified transplantation technique does not require a particular organ explantation procedure and can be applied for all liver and kidney grafts.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Riñón / Riñón Poliquístico Autosómico Dominante Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Langenbecks Arch Surg Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Riñón / Riñón Poliquístico Autosómico Dominante Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Langenbecks Arch Surg Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania