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Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules.
Vissol-Gaudin, Eléonore; Pearson, Chris; Groves, Chris; Zeze, Dagou A; Cantiello, Horacio F; Cantero, María Del Rocio; Petty, Michael C.
Afiliación
  • Vissol-Gaudin E; Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.
  • Pearson C; Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.
  • Groves C; Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.
  • Zeze DA; Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.
  • Cantiello HF; Laboratorio de Canales Iónicos, Instituto Multidisciplinario de Salud, Tecnología Y Desarrollo (IMSaTeD, CONICET-UNSE), Villa El Zanjón, 4206, Santiago del Estero, Argentina.
  • Cantero MDR; Laboratorio de Canales Iónicos, Instituto Multidisciplinario de Salud, Tecnología Y Desarrollo (IMSaTeD, CONICET-UNSE), Villa El Zanjón, 4206, Santiago del Estero, Argentina.
  • Petty MC; Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK. m.c.petty@durham.ac.uk.
Sci Rep ; 11(1): 10776, 2021 05 24.
Article en En | MEDLINE | ID: mdl-34031499
We report on the electrical behaviour of thin films of bovine brain microtubules (MTs). For samples in both their dried and hydrated states, the measured currents reveal a power law dependence on the applied DC voltage. We attribute this to the injection of space-charge from the metallic electrode(s). The MTs are thought to form a complex electrical network, which can be manipulated with an applied voltage. This feature has been exploited to undertake some experiments on the use of the MT mesh as a medium for computation. We show that it is possible to evolve MT films into binary classifiers following an evolution in materio approach. The accuracy of the system is, on average, similar to that of early carbon nanotube classifiers developed using the same methodology.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Microtúbulos Límite: Animals Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Microtúbulos Límite: Animals Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido