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A study of breastfeeding practices, SARS-CoV-2 and its antibodies in the breast milk of mothers confirmed with COVID-19.
Peng, Sicong; Zhu, Huaping; Yang, Lixia; Cao, Li; Huang, Xiaona; Dynes, Michelle; Narayan, Anuradha; Xia, Jianbo; Chen, Yang; Zhang, Pei; Liu, Hongyan; Li, Hua; Xia, Shiwen.
Afiliación
  • Peng S; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Zhu H; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Yang L; Department of Neonatology, Xiaochang First People's Hospital, Xiaochang, Hubei, China.
  • Cao L; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Huang X; Health, Nutrition and WASH, UNICEF China, Beijing, China.
  • Dynes M; UNICEF East Asia and Pacific Regional Office, Bangkok, Thailand.
  • Narayan A; Health, Nutrition and WASH, UNICEF China, Beijing, China.
  • Xia J; Department of Laboratory Medicine, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei, China.
  • Chen Y; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Zhang P; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Liu H; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Li H; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
  • Xia S; Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei 430070, China.
Lancet Reg Health West Pac ; 4: 100045, 2020 Nov.
Article en En | MEDLINE | ID: mdl-34013217
BACKGROUND: The possibility of 2019 novel coronavirus disease (COVID-19) transmission to neonates through breast milk remains unverified. METHODS: This paper presents the interim results of a longitudinal study being carried out in Hubei province. As of 1 April 2020, 24 mothers confirmed with COVID-19, 19 mothers suspected with COVID-19 but Polymerase chain reaction negative, and 21 mothers without COVID-19 and their neonates have been recruited. Telephone follow-up was conducted to collect information on breastfeeding practices. Forty-four breast milk samples were collected from 16 of the 24 mothers with confirmed COVID-19 for the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) and antibodies (IgM and IgG) testing. FINDINGS: The average mother-child separation time was 36•7 ± 21•1 days among mothers confirmed with COVID-19, significantly longer than that of the suspected group (16•6 ± 13•1 days) and control group (10•5 ± 8•2 days). Both the COVID-19 confirmed (58•3%) and suspected (52•6%) groups presented significantly lower rates of breastfeeding as compared with the control group (95•2%). All 44 breast milk samples tested negative for the SARS-CoV-2 nucleic acid. Thirty-eight breast milk samples underwent antibody testing and all tested negative for IgG. Twenty-one breast milk samples from 8 women tested positive for IgM, while the remaining samples from 11 women tested negative. INTERPRETATION: Considering the lack of evidence for SARS-CoV-2 transmission through breast milk, breastfeeding counselling along with appropriate hand hygiene precautions and facemasks should be provided to all pregnant women. FUNDING: The study was funded by the Hong Kong Committee for UNICEF.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies Idioma: En Revista: Lancet Reg Health West Pac Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies Idioma: En Revista: Lancet Reg Health West Pac Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido