Does the intact nephron hypothesis provide a reasonable model for metformin dosing in chronic kidney disease?

Pradhan, Sudeep; Duffull, Stephen B; Wilson, Luke C; Kuan, Isabelle H S; Walker, Robert J; Putt, Tracey L; Schollum, John B W; Wright, Daniel F B

Pradhan, Sudeep; Duffull, Stephen B; Wilson, Luke C; Kuan, Isabelle H S; Walker, Robert J; Putt, Tracey L; Schollum, John B W; Wright, Daniel F B.

Afiliación

Pradhan S; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Duffull SB; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Wilson LC; Department of Medicine, University of Otago, Dunedin, New Zealand.
Kuan IHS; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Walker RJ; Department of Medicine, University of Otago, Dunedin, New Zealand.
Putt TL; Department of Medicine, University of Otago, Dunedin, New Zealand.
Schollum JBW; Department of Medicine, University of Otago, Dunedin, New Zealand.
Wright DFB; School of Pharmacy, University of Otago, Dunedin, New Zealand.

Br J Clin Pharmacol ; 87(12): 4868-4876, 2021 12.

Article en En | MEDLINE | ID: mdl-34004027

Asunto(s)

Metformina; Insuficiencia Renal Crónica; Creatinina; Tasa de Filtración Glomerular; Humanos; Riñón; Pruebas de Función Renal; Nefronas; Insuficiencia Renal Crónica/tratamiento farmacológico

Palabras clave

NONMEM; chronic kidney disease; intact nephron hypothesis; metformin; pharmacokinetics

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Metformina Límite: Humans Idioma: En Revista: Br J Clin Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google