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A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks.
Yuan, Chongze; Chen, Haojie; Tu, Shiqi; Huang, Hsin-Yi; Pan, Yunjian; Gui, Xiuqi; Kuang, Muyu; Shen, Xuxia; Zheng, Qiang; Zhang, Yang; Cheng, Chao; Hong, Hui; Tao, Xiaoting; Peng, Yizhou; Yao, Xingxin; Meng, Feilong; Ji, Hongbin; Shao, Zhen; Sun, Yihua.
Afiliación
  • Yuan C; Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Chen H; Institute of Thoracic Oncology, Fudan University, Shanghai, 200032, China.
  • Tu S; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Huang HY; CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Pan Y; CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Gui X; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Kuang M; Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Shen X; Institute of Thoracic Oncology, Fudan University, Shanghai, 200032, China.
  • Zheng Q; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Zhang Y; CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Cheng C; Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Hong H; Institute of Thoracic Oncology, Fudan University, Shanghai, 200032, China.
  • Tao X; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Peng Y; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Yao X; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Meng F; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Ji H; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Shao Z; Department of Thoracic Surgery and State Key Laboratory of Genetic Engineering, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Sun Y; Institute of Thoracic Oncology, Fudan University, Shanghai, 200032, China.
Genome Biol ; 22(1): 156, 2021 05 17.
Article en En | MEDLINE | ID: mdl-34001209
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Redes Reguladoras de Genes / Epigenómica / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Redes Reguladoras de Genes / Epigenómica / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido