Your browser doesn't support javascript.
loading
Outcome and postoperative complications in 73 dogs with thyroid carcinoma with gross vascular invasion managed with thyroidectomy.
Latifi, Max; Skinner, Owen T; Spoldi, Elisa; Ackerman, Leah; Souza, Carlos H De M; Yoon, Jin; Vinayak, Arathi; Tuohy, Joanne L; Wallace, Mandy L; Dornbusch, Josephine A; Selmic, Laura E; Menard, Jenna; Sumner, Julia P; Schrock, Kelly C; Wustefeld-Janssens, Brandan G; Matz, Brad M; Daniel, Todd E; Mickelson, Megan A.
Afiliación
  • Latifi M; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
  • Skinner OT; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
  • Spoldi E; Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
  • Ackerman L; Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
  • Souza CHM; Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
  • Yoon J; Surgical Oncology Department, VCA West Coast Specialty and Emergency Animal Hospital, Fountain Valley, California, USA.
  • Vinayak A; Surgical Oncology Department, VCA West Coast Specialty and Emergency Animal Hospital, Fountain Valley, California, USA.
  • Tuohy JL; Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Blacksburg, Virginia, USA.
  • Wallace ML; Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
  • Dornbusch JA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Selmic LE; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Menard J; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
  • Sumner JP; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
  • Schrock KC; Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biosciences, Texas A&M University, College Station, Texas, USA.
  • Wustefeld-Janssens BG; Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biosciences, Texas A&M University, College Station, Texas, USA.
  • Matz BM; Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
  • Daniel TE; Department of Information Technology and Cybersecurity, College of Business, Missouri State University, Springfield, Missouri, USA.
  • Mickelson MA; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA.
Vet Comp Oncol ; 19(4): 685-696, 2021 Dec.
Article en En | MEDLINE | ID: mdl-33993605
Excellent outcomes have been reported following thyroidectomy for thyroid carcinoma in dogs, but outcomes for thyroid carcinomas with gross vascular invasion are poorly described. This study describes the clinical outcomes and complications in dogs with thyroid carcinomas with gross vascular invasion undergoing thyroidectomy. Medical records of dogs that underwent thyroidectomy between January 1st 2010 and December 31st 2019 were reviewed at 10 hospitals. Signalment, diagnostic data, primary and adjuvant treatments performed, and outcome were abstracted. Survival was calculated using Kaplan-Meier analysis. Multiple logistic regression was used to identify variables associated with disease-specific survival. Seventy-three dogs were included, of which 58 underwent unilateral thyroidectomy and 15 underwent bilateral thyroidectomy. Complications were reported in five dogs (three major, two minor; 6.8%) intraoperatively and 12 dogs (two major leading to death, 10 minor; 16.4%) postoperatively. Seven (9.6%) dogs developed locoregional recurrence at a median of 238 days postoperatively (range: 15-730 days). Distant metastasis was suspected or confirmed in nine dogs (12.3%) at a median of 375 days postoperatively (range: 50-890 days). Twenty-seven dogs (37%) received adjuvant therapy (chemotherapy: n = 21; radiotherapy: n = 6). Thirty-nine dogs were euthanized or died, with 20 deaths related to disease (n = 10) or of unknown cause (n = 10), 19 due to unrelated causes, and nine lost to follow-up. Median overall and disease-specific survival were 621 days and not reached respectively. One-year disease-specific survival rate was 82.5%. No variables were associated with disease-specific survival in our dataset. Surgery may be considered for loco-regional therapy in dogs with thyroid carcinoma with gross vascular invasion.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Neoplasias de la Tiroides / Enfermedades de los Perros Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Vet Comp Oncol Asunto de la revista: MEDICINA VETERINARIA / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Neoplasias de la Tiroides / Enfermedades de los Perros Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Vet Comp Oncol Asunto de la revista: MEDICINA VETERINARIA / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido