Thymoquinone sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis via oxidative DNA damage.

Zhang, Ruikui; Wu, Tao; Zheng, Peipei; Liu, Ming; Xu, Guixiang; Xi, Ming; Yu, Jian

Zhang, Ruikui; Wu, Tao; Zheng, Peipei; Liu, Ming; Xu, Guixiang; Xi, Ming; Yu, Jian.

Afiliación

Zhang R; Department of Special Emergency Surgery, Special Medical Center of Chinese People 's Armed Police Forces, Tianjin, 300162, China.
Wu T; Department of Infectious Disease, Hainan General Hospital, Haikou, Hainan, 570311, China.
Zheng P; Department of General Surgery, the First Hospital Affiliated of Shandong First Medical University (Qianfoshan Hospital), Jinan, Shandong, 250014, China.
Liu M; Department of Infectious Disease, Hainan General Hospital, Haikou, Hainan, 570311, China.
Xu G; Department of General Surgery, Qingdao Fuwai Hospital Qingdao, Shandong, 266034, China.
Xi M; Department of Urology, Huadu District People's Hospital, Southern Medical University, Guangzhou, Guangdong, 510800, China.
Yu J; Department of General Surgery, the First Hospital Affiliated of Shandong First Medical University (Qianfoshan Hospital), Jinan, Shandong, 250014, China. Electronic address: yujianhcc2020@sina.com.

DNA Repair (Amst) ; 103: 103117, 2021 07.

Article en En | MEDLINE | ID: mdl-33990030

Asunto(s)

Apoptosis; Benzoquinonas/farmacología; Carcinoma Hepatocelular/tratamiento farmacológico; Daño del ADN; Neoplasias Hepáticas/tratamiento farmacológico; Ligando Inductor de Apoptosis Relacionado con TNF/metabolismo; Benzoquinonas/uso terapéutico; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Carcinoma Hepatocelular/fisiopatología; ADN/efectos de los fármacos; Células Hep G2; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/fisiopatología; Estrés Oxidativo

Palabras clave

Apoptosis; DNA damage; Hepatocellular carcinoma; TRAIL

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Daño del ADN / Benzoquinonas / Apoptosis / Carcinoma Hepatocelular / Ligando Inductor de Apoptosis Relacionado con TNF / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: DNA Repair (Amst) Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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