Your browser doesn't support javascript.
loading
Effect of gestational age at birth, sex, and race on foveal structure in children.
Jin, Jing; Friess, Amanda; Hendricks, Dorothy; Lehman, Sharon; Salvin, Jonathan; Reid, Julia E; Wang, Jingyun.
Afiliación
  • Jin J; Department of Pediatric Ophthalmology, Nemours/Alfred I. duPont Hospital for Children, P.O. Box 296, Wilmington, DE, 19899, USA. Jing.jin@nemours.org.
  • Friess A; Department of Pediatric Ophthalmology, Nemours/Alfred I. duPont Hospital for Children, P.O. Box 296, Wilmington, DE, 19899, USA.
  • Hendricks D; Department of Pediatric Ophthalmology, Nemours/Alfred I. duPont Hospital for Children, P.O. Box 296, Wilmington, DE, 19899, USA.
  • Lehman S; Department of Pediatric Ophthalmology, Nemours/Alfred I. duPont Hospital for Children, P.O. Box 296, Wilmington, DE, 19899, USA.
  • Salvin J; Department of Pediatric Ophthalmology, Nemours/Alfred I. duPont Hospital for Children, P.O. Box 296, Wilmington, DE, 19899, USA.
  • Reid JE; Department of Pediatric Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Wang J; Department of Biological and Vision Sciences, State University of New York College of Optometry, New York, NY, USA.
Graefes Arch Clin Exp Ophthalmol ; 259(10): 3137-3148, 2021 Oct.
Article en En | MEDLINE | ID: mdl-33961109
PURPOSE: Premature birth, race, and sex are contributing risk factors for retinopathy of prematurity (ROP) and have long-term impact on children's retinal structure. Few studies investigate impact of race and sex on macular structure in children born preterm. This study compared foveal structure in preterm and full-term children. METHODS: Children aged 4-18 years were enrolled into three groups: (1) ROP-risk group (n = 81), born at < 32 weeks gestational age with and without history of ROP; (2) preterm group (n = 46), born at 32-36 weeks gestational age; and (3) control group (n = 68) with full-term birth. Using spectral-domain optical coherence tomography volume-scan images, foveal structure within 1-mm and 3-mm early treatment diabetic retinopathy study circular grid was measured and segmented. Total inner and outer retina thickness of the right eye was compared among the three groups. RESULTS: The mean total foveal thickness (in microns) was 287 ± 26 for the ROP-risk group, 276 ± 19 for the preterm group, and 263 ± 20 for the control group (F = 26, p < 0.001). Foveal thickness of the ROP-risk group was significantly higher than that of the preterm group and the control group (all p < 0.05). Foveal thickness was thinner in black children than in white children and thinner in females than in males (all p < 0.001). A similar disparity in race and sex was found in the thickness of the inner and outer layers. CONCLUSIONS: The fovea was significantly thicker in the ROP-risk group than the control group. Foveal thickness decreases with increased gestational age. Race and sex are significant factors in foveal structure in children.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retinopatía de la Prematuridad / Recien Nacido Prematuro Tipo de estudio: Diagnostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Child / Female / Humans / Male / Newborn / Pregnancy Idioma: En Revista: Graefes Arch Clin Exp Ophthalmol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retinopatía de la Prematuridad / Recien Nacido Prematuro Tipo de estudio: Diagnostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Child / Female / Humans / Male / Newborn / Pregnancy Idioma: En Revista: Graefes Arch Clin Exp Ophthalmol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania