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13N-Ammonia myocardial blood flow quantitation in patient with aneurismal coronary artery disease.
Plata-Corona, Juan Carlos; Carvajal-Juarez, Isabel; Espinola-Zavaleta, Nilda; Damas-De Los Santos, Felix; Rivera-Bravo, Belen; Alexanderson-Rosas, Erick.
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  • Plata-Corona JC; Clinical Cardiology Department, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.
  • Carvajal-Juarez I; Nuclear Cardiology Department, National Institute of Cardiology Ignacio Chavez, Juan Badiano Nº 1, Colonia Seccion XVI, Tlalpan, P.C 14080, Mexico City, Mexico.
  • Espinola-Zavaleta N; Nuclear Medicine Department, UMAE, Cardiology Hospital, CMNSXXI, Mexico City, Mexico.
  • Damas-De Los Santos F; Nuclear Cardiology Department, National Institute of Cardiology Ignacio Chavez, Juan Badiano Nº 1, Colonia Seccion XVI, Tlalpan, P.C 14080, Mexico City, Mexico.
  • Rivera-Bravo B; Echocardiography Department, ABC Medical Center, Mexico City, Mexico.
  • Alexanderson-Rosas E; Hemodynamics Department, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.
J Nucl Cardiol ; 29(4): 1826-1831, 2022 08.
Article en En | MEDLINE | ID: mdl-33959843
Aneurysmal coronary artery disease includes coronary artery aneurysms and ectasia; this condition has been associated with poor long-term outcomes. Few studies have explored myocardial blood flow 13N-ammonia PET/CT MPI added value. We present a 45-year-old man who came to the emergency department with chest pain. After a physical examination and laboratory studies, he was diagnosed with very high-risk unstable angina and referred to the catheterization laboratory. Coronary angiography showed the culprit lesion in the LCx and was treated by angioplasty and stent. LAD was found with coronary artery ectasia (TIMI 2 flow grade) and the RCA with aneurysmal disease in the proximal and middle segments (TIMI 3 flow grade). Medical treatment was decided for these findings and the patient was discharged. Two weeks later, we performed a 13N-ammonia PET/CT MPI founding apical, inferior, and inferoseptal severe ischemia, and reduced hyperemic coronary blood flow and coronary flow reserve in the RCA territory. Flow was normal in the LAD territory. Although coronary angiography remains the gold standard for evaluating these coronary abnormalities, it does not show the physiological compromise. Therefore 13N-ammonia PET/CT MPI should be performed as a complementary noninvasive imaging approach.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria Límite: Humans / Male / Middle aged Idioma: En Revista: J Nucl Cardiol Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: México Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria Límite: Humans / Male / Middle aged Idioma: En Revista: J Nucl Cardiol Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: México Pais de publicación: Estados Unidos