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Outcomes of Patients With ST-Segment Elevation Myocardial Infarction Admitted During COVID-19 Pandemic Lockdown in Germany - Results of a Single Center Prospective Cohort Study.
Rattka, Manuel; Stuhler, Lina; Winsauer, Claudia; Dreyhaupt, Jens; Thiessen, Kevin; Baumhardt, Michael; Markovic, Sinisa; Rottbauer, Wolfgang; Imhof, Armin.
Afiliación
  • Rattka M; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Stuhler L; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Winsauer C; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Dreyhaupt J; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
  • Thiessen K; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Baumhardt M; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Markovic S; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Rottbauer W; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
  • Imhof A; Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.
Front Cardiovasc Med ; 8: 638954, 2021.
Article en En | MEDLINE | ID: mdl-33959641
Objective: Since the outbreak of the COVID-19 pandemic, healthcare professionals reported declining numbers of patients admitted with ST-segment myocardial infarction (STEMI) associated with increased in-hospital morbidity and mortality. However, the effect of lockdown on outcomes of STEMI patients admitted during the COVID-19 crisis has not been prospectively evaluated. Methods: A prospective, observational study on STEMI patients admitted to our tertiary care center during the COVID-19 pandemic was conducted. Outcomes of patients admitted during lockdown were compared to those patients admitted before and after pandemic-related lockdown. Results: A total of 147 patients were enrolled in our study, including 57 patients in the pre-lockdown group (November 1, 2019 to March 20, 2020), 16 patients in the lockdown group (March 21 to April 19, 2020), and 74 patients in the post-lockdown group (April 20 to September 30, 2020). Patients admitted during lockdown had significantly longer time to first medical contact, longer door-to-needle-time, higher serum troponin T levels, worse left ventricular end-diastolic pressure, and higher need for circulatory support. After a median follow-up of 142 days, survival was significantly worse in STEMI patients of the lockdown group (log-rank: p = 0.0035). Conclusions: This is the first prospective study on outcomes of STEMI patients admitted during public lockdown amid the COVID-19 pandemic. Our results suggest that lockdown might deteriorate outcomes of STEMI patients. Public health strategies to constrain spread of COVID-19, such as lockdown, have to be accompanied by distinct public instructions to ensure timely medical care in acute diseases such as STEMI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Front Cardiovasc Med Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Front Cardiovasc Med Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza