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Absorption, metabolism and excretion of pictilisib, a potent pan-class I phosphatidylinositol-3-Kinase (PI3K) inhibitor, in rats, dogs, and humans.
Yue, Qin; Khojasteh, S Cyrus; Cho, Sungjoon; Ma, Shuguang; Mulder, Teresa; Chen, John; Pang, Jodie; Ding, Xiao; Deese, Alan; Pellet, Jackson D; Siebers, Nicholas; Joas, Lori; Salphati, Laurent; Ware, Joseph A.
Afiliación
  • Yue Q; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Khojasteh SC; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Cho S; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Ma S; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Mulder T; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Chen J; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Pang J; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Ding X; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Deese A; Small Molecule Pharmaceutical Sciences, Genentech Inc, South San Francisco, CA, USA.
  • Pellet JD; Small Molecule Pharmaceutical Sciences, Genentech Inc, South San Francisco, CA, USA.
  • Siebers N; Covance Clinical Research Unit, 3402 Kinsman Boulevard, Madison, WI, USA.
  • Joas L; Covance Clinical Research Unit, 3402 Kinsman Boulevard, Madison, WI, USA.
  • Salphati L; Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA.
  • Ware JA; Clinical Pharmacology, Genentech Inc, South San Francisco, CA, USA.
Xenobiotica ; 51(7): 796-810, 2021 Jul.
Article en En | MEDLINE | ID: mdl-33938357
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Indazoles Límite: Animals / Humans Idioma: En Revista: Xenobiotica Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Indazoles Límite: Animals / Humans Idioma: En Revista: Xenobiotica Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido