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Efficacy and safety of infrahepatic inferior vena cava clamping under controlled central venous pressure for reducing blood loss during hepatectomy: A randomized controlled trial.
Junrungsee, Sunhawit; Suwannikom, Karnpichamonch; Tiyaprasertkul, Worakamol; Lapisatepun, Worakitti; Chotirosniramit, Anon; Sandhu, Trichak; Chandacham, Kamtone; Jirapongcharoenlap, Tidarat; Lapisatepun, Warangkana; Ko-Iam, Wasana.
Afiliación
  • Junrungsee S; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Suwannikom K; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Tiyaprasertkul W; Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Lapisatepun W; Bangkok Hospital Chiang Mai, Chiang Mai, Thailand.
  • Chotirosniramit A; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Sandhu T; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Chandacham K; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Jirapongcharoenlap T; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Lapisatepun W; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • Ko-Iam W; Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
J Hepatobiliary Pancreat Sci ; 28(7): 604-616, 2021 Jul.
Article en En | MEDLINE | ID: mdl-33905606
BACKGROUND: The purpose of this study was to evaluate the effectiveness and safety of inferior vena cava (IVC) clamping for reducing blood loss during hepatectomy. METHODS: In total, 120 elective hepatectomy patients who underwent surgery from May 2016 to October 2017 were enrolled and randomized into the IVC clamping group or nonclamping group. Both groups were managed by anesthesiological techniques for CVP reduction. Blood loss and clinical parameters were analyzed for 30 days after surgery. RESULTS: Fifty-nine patients were assigned to the IVC clamping group and 61 to the non-IVC clamping group. There was a significant difference in the total blood loss between both groups, with less blood loss observed in the IVC clamping group [500 vs 600 mL, P = .006]. The transection blood loss in the IVC clamping group was also significantly lower than that in the non-IVC clamping group [300 vs 500 mL, P < .001]. However, CVP was not associated with blood loss volume. Postoperative outcomes were not significant in either group. CONCLUSIONS: IVC clamping is beneficial for reducing blood loss during hepatectomy and is safe when combined with anesthesiological techniques. If feasible, this technique should be used regardless of the CVP value.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vena Cava Inferior / Hepatectomía Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: J Hepatobiliary Pancreat Sci Año: 2021 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vena Cava Inferior / Hepatectomía Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: J Hepatobiliary Pancreat Sci Año: 2021 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Japón