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Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide.
Hirschberg, Angelica Lindén; Bitzer, Johannes; Cano, Antonio; Ceausu, Iuliana; Chedraui, Peter; Durmusoglu, Fatih; Erkkola, Risto; Goulis, Dimitrios G; Kiesel, Ludwig; Lopes, Patrice; Pines, Amos; van Trotsenburg, Mick; Lambrinoudaki, Irene; Rees, Margaret.
Afiliación
  • Hirschberg AL; Department of Women's and Children's Health, Karolinska Institutet and Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden. Electronic address: angelica.linden-hirschberg@sll.se.
  • Bitzer J; Department of Obstetrics and Gynecology, University Hospital, Basel, Switzerland.
  • Cano A; Department of Pediatrics, Obstetrics and Gynecology, University of Valencia and INCLIVA, Valencia, Spain.
  • Ceausu I; Department of Obstetrics and Gynecology I, "Carol Davila" University of Medicine and Pharmacy, "Dr. I. Cantacuzino" Clinical Hospital, Bucharest, Romania.
  • Chedraui P; Instituto de Investigación e Innovación de Salud Integral (ISAIN), Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.
  • Durmusoglu F; Istanbul Medipol International School of Medicine, Istanbul, Turkey.
  • Erkkola R; Department of Obstetrics and Gynecology, University Central Hospital, Turku, Finland.
  • Goulis DG; Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Greece.
  • Kiesel L; Department of Gynecology and Obstetrics, University of Münster, Münster, Germany.
  • Lopes P; Polyclinique de l'Atlantique Saint Herblain, F 44819 St Herblain France and Université de Nantes F 44093 Nantes Cedex, France.
  • Pines A; Sackler Faculty of Medicine, Tel-Aviv University, Israel.
  • van Trotsenburg M; Department of Obstetrics and Gynecology, University Hospital St. Poelten-Lilienfeld, Austria.
  • Lambrinoudaki I; Second Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Greece.
  • Rees M; Women's Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Maturitas ; 148: 55-61, 2021 Jun.
Article en En | MEDLINE | ID: mdl-33896654
INTRODUCTION: Vulvovaginal atrophy (VVA) is a chronic condition caused by estrogen deficiency. It affects around 50% of postmenopausal women, reducing their general and sexual quality of life as well as the quality of their personal relationships. AIM: The aim of this clinical guide is to set out an individualized approach to the management of VVA with topical estrogens and non-hormonal preparations. MATERIALS AND METHODS: Literature review and consensus of expert opinion. SUMMARY RECOMMENDATIONS: An individualized approach is required for the management of VVA. Topical low-dose estrogens are effective and also alleviate urinary incontinence and prevent recurrent urinary tract infections. Women should not be denied long-term use of topical estrogens as long as they feel that this treatment is of benefit to them, because the safety data are reassuring. Non-hormonal preparations (lubricants and moisturizers) should be the first-line treatment for VVA in women taking adjuvant endocrine therapies for cancers considered to be hormone-dependent. They can be used over the long term.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Atrofia / Enfermedades Vaginales / Enfermedades de la Vulva / Guías de Práctica Clínica como Asunto / Posmenopausia / Estrógenos Tipo de estudio: Guideline Aspecto: Patient_preference Límite: Female / Humans Idioma: En Revista: Maturitas Año: 2021 Tipo del documento: Article Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Atrofia / Enfermedades Vaginales / Enfermedades de la Vulva / Guías de Práctica Clínica como Asunto / Posmenopausia / Estrógenos Tipo de estudio: Guideline Aspecto: Patient_preference Límite: Female / Humans Idioma: En Revista: Maturitas Año: 2021 Tipo del documento: Article Pais de publicación: Irlanda