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Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
Gorecki, Lukas; Misiachna, Anna; Damborsky, Jiri; Dolezal, Rafael; Korabecny, Jan; Cejkova, Lada; Hakenova, Kristina; Chvojkova, Marketa; Karasova, Jana Zdarova; Prchal, Lukas; Novak, Martin; Kolcheva, Marharyta; Kortus, Stepan; Vales, Karel; Horak, Martin; Soukup, Ondrej.
Afiliación
  • Gorecki L; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Misiachna A; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic; Department of Physiology, Faculty of Science, Charles University in Prague, A
  • Damborsky J; Loschmidt Laboratories, Department of Experimental Biology and RECETOX, Masaryk University, Kamenice 5/A4, 625 00, Brno, Czech Republic; International Centre for Clinical Research, St. Anne's University Hospital, Pekarska 53, 656 91 Brno, Czech Republic.
  • Dolezal R; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Korabecny J; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Cejkova L; National Institute of Mental Health, Topolová 748, 250 67, Klecany, Czech Republic.
  • Hakenova K; National Institute of Mental Health, Topolová 748, 250 67, Klecany, Czech Republic.
  • Chvojkova M; National Institute of Mental Health, Topolová 748, 250 67, Klecany, Czech Republic.
  • Karasova JZ; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
  • Prchal L; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Novak M; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Kralove, Charles University, Heyrovskeho, 1203, Hradec Kralove, Czech Republic.
  • Kolcheva M; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic.
  • Kortus S; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic.
  • Vales K; National Institute of Mental Health, Topolová 748, 250 67, Klecany, Czech Republic.
  • Horak M; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague 4, Czech Republic. Electronic address: martin.horak@iem.cas.cz.
  • Soukup O; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. Electronic address: ondrej.soukup@fnhk.cz.
Eur J Med Chem ; 219: 113434, 2021 Jul 05.
Article en En | MEDLINE | ID: mdl-33892271
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tacrina / Inhibidores de la Colinesterasa / Receptores de N-Metil-D-Aspartato Límite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tacrina / Inhibidores de la Colinesterasa / Receptores de N-Metil-D-Aspartato Límite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Francia