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Review on the recent progress in the development of fluorescent probes targeting enzymes.
Rajapaksha, Asanka Amith; Fu, Yi-Xuan; Guo, Wu Yingzheng; Liu, Shi-Yu; Li, Zhi-Wen; Xiong, Cui-Qin; Yang, Wen-Chao; Yang, Guang-Fu.
Afiliación
  • Rajapaksha AA; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China.
  • Fu YX; Department of Nano Science Technology, Faculty of Technology, Wayamba University of Sri Lanka, Kuliyapitiya, Sri Lanka.
  • Guo WY; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China.
  • Liu SY; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China.
  • Li ZW; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China.
  • Xiong CQ; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China.
  • Yang WC; Department of Interventional Medicine, Wuhan Third Hospital-Tongren Hospital of Wuhan University, Wuhan 430070, People's Republic of China.
  • Yang GF; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China.
Methods Appl Fluoresc ; 9(3)2021 Apr 30.
Article en En | MEDLINE | ID: mdl-33873170
Enzymes are very important for biological processes in a living being, performing similar or multiple tasks in and out of cells, tissues and other organisms at a particular location. The abnormal activity of particular enzyme usually caused serious diseases such as Alzheimer's disease, Parkinson's disease, cancers, diabetes, cardiovascular diseases, arthritis etc. Hence, nondestructive and real-time visualization for certain enzyme is very important for understanding the biological issues, as well as the drug administration and drug metabolism. Fluorescent cellular probe-based enzyme detectionin vitroandin vivohas become broad interest for human disease diagnostics and therapeutics. This review highlights the recent findings and designs of highly sensitive and selective fluorescent cellular probes targeting enzymes for quantitative analysis and bioimaging.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sondas Moleculares / Enzimas / Colorantes Fluorescentes Límite: Animals / Humans Idioma: En Revista: Methods Appl Fluoresc Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sondas Moleculares / Enzimas / Colorantes Fluorescentes Límite: Animals / Humans Idioma: En Revista: Methods Appl Fluoresc Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido