Your browser doesn't support javascript.
loading
Yin and yang of immunological memory in controlling infections: Overriding self defence mechanisms.
Roy, Roshan Kumar; Yadav, Rakhi; Jain, Aklank; Tripathi, Vishwas; Jain, Manju; Singh, Sandhya; Prakash, Hridayesh.
Afiliación
  • Roy RK; Amity Institute of Virology and Immunology, Amity University, Noida, India.
  • Yadav R; Amity Institute of Virology and Immunology, Amity University, Noida, India.
  • Jain A; Department of Zoology, Central University of Punjab, Bathinda, Punjab, India.
  • Tripathi V; School of Biotechnology, Gautam Buddha University, Gautam Buddha Nagar, India.
  • Jain M; Department of Biochemistry, Central University of Punjab, Bathinda, Punjab, India.
  • Singh S; Amity Institute of Physiology and Allied Sciences, Amity University, Noida, India.
  • Prakash H; Amity Institute of Virology and Immunology, Amity University, Noida, India.
Int Rev Immunol ; 41(2): 240-252, 2022.
Article en En | MEDLINE | ID: mdl-33872093
Immunological memory is critical for host immunity and decisive for individual to respond exponentially to previously encountered infection. Both T and B cell memory are known to orchestrate immunological memory with their central and effector memory arms contributing in prolonged immunity/defence mechanisms of host. While central memory helps in maintaining prolonged immunity for a particular infection, effector memory helps in keeping local/seasonal infection in control. In addition to this, generation of long-lived plasma cells is pivotal for generating neutralizing antibodies which can enhance recall and B cell memory to control re-infection. In view of this, scaling up memory response is one of the major objectives for the expected outcome of vaccination. In this line, this review deals with the significance of memory cells, molecular pathways of their development, maintenance, epigenetic regulation and negative regulation in various infections. We have also highlighted the significance of both T and B cell memory responses in the vaccination approaches against range of infections which is not fully explored so far.[Box: see text].
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epigénesis Genética / Memoria Inmunológica Límite: Humans Idioma: En Revista: Int Rev Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epigénesis Genética / Memoria Inmunológica Límite: Humans Idioma: En Revista: Int Rev Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido