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Analysis of Epidemiological and Clinical Characteristics of COVID-19 in Northwest Mexico and the Relationship Between the Influenza Vaccine and the Survival of Infected Patients.
Angulo-Zamudio, Uriel A; Martínez-Villa, Francisco M; Leon-Sicairos, Nidia; Flores-Villaseñor, Hector; Velazquez-Roman, Jorge; Campos-Romero, Abraham; Alcántar-Fernández, Jonathan; Urrea, Francisco; Muro-Amador, Secundino; Medina-Serrano, Julio; Martinez-Garcia, Jesus J; Sanchez-Cuen, Jaime; Angulo-Rocha, Jorge; Canizalez-Roman, Adrian.
Afiliación
  • Angulo-Zamudio UA; Centro de Investigación Aplicada a la Salud Pública (CIASaP), School of Medicine, Autonomous University of Sinaloa, Culiacan, Mexico.
  • Martínez-Villa FM; Programa de Maestría en Ciencias en Biomedicina Molecular, Autonomous University of Sinaloa (UAS), Culiacan, Mexico.
  • Leon-Sicairos N; Unidad de Medicina Familiar No. 46, Instituto Mexicano del Seguro Social (IMSS), Culiacan, Mexico.
  • Flores-Villaseñor H; Centro de Investigación Aplicada a la Salud Pública (CIASaP), School of Medicine, Autonomous University of Sinaloa, Culiacan, Mexico.
  • Velazquez-Roman J; Pediatric Hospital of Sinaloa, Culiacan, Mexico.
  • Campos-Romero A; Centro de Investigación Aplicada a la Salud Pública (CIASaP), School of Medicine, Autonomous University of Sinaloa, Culiacan, Mexico.
  • Alcántar-Fernández J; The Sinaloa State Public Health Laboratory, Secretariat of Health, Culiacan, Mexico.
  • Urrea F; Centro de Investigación Aplicada a la Salud Pública (CIASaP), School of Medicine, Autonomous University of Sinaloa, Culiacan, Mexico.
  • Muro-Amador S; Salud Digna A.C., Culiacán, Mexico.
  • Medina-Serrano J; Salud Digna A.C., Culiacán, Mexico.
  • Martinez-Garcia JJ; Hospital Regional, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Culiacán, Mexico.
  • Sanchez-Cuen J; Centro de Investigación Aplicada a la Salud Pública (CIASaP), School of Medicine, Autonomous University of Sinaloa, Culiacan, Mexico.
  • Angulo-Rocha J; Coordinación en Investigación en Salud, Órgano de Operación Administrativa Desconcentrada (OOAD), Instituto Mexicano del Seguro Social (IMSS), Culiacan Sinaloa, Mexico.
  • Canizalez-Roman A; Centro de Investigación Aplicada a la Salud Pública (CIASaP), School of Medicine, Autonomous University of Sinaloa, Culiacan, Mexico.
Front Public Health ; 9: 570098, 2021.
Article en En | MEDLINE | ID: mdl-33842415
The first cases of unexplained pneumonia were reported in Wuhan, China, in December of 2019. Later, a novel coronavirus (SARS-CoV-2) was identified as the causal agent of pneumonia. This virus has since spread to more than 180 countries and has been declared a pandemic by the World Health Organization. Herein, we aimed to determine the epidemiological and clinical characteristics of symptomatic patients with coronavirus disease 2019 (COVID-19) and the relationship between the influenza vaccine with a lower risk of severe COVID-19 infection in the state of Sinaloa. We collected demographic and clinical data of 4,040 patients with acute respiratory infections across Sinaloa state hospitals from February 28 to May 15, 2020. The prevalence of COVID-19 among hospitalized patients with respiratory symptoms in Sinaloa showed 45.2% of men were more affected than women (p < 0.001), and people aged 40-49 years were the most affected. The main symptoms of COVID-19 infection were cough and fever (p < 0.001), while hypertension, obesity, and type 2 diabetes were the chronic diseases associated with COVID-19 than non-COVID-19 (p < 0.003). Healthcare workers were most likely to be infected compared to other occupations (p < 0.001). The general lethality rate was 14.1%, and males >62 years were the ones who had a higher lethality rate (p < 0.001); the aforementioned chronic diseases were related to higher lethality of COVID-19 (p < 0.001). Likewise, higher lethality was seen in housewives and patient retirees/pensioners compared with other occupations (p < 0.001). Finally, we found there was a relationship between influenza vaccination and a lower risk of severe COVID-19 infection and mortality (p < 0.001). These findings showed that healthcare workers, men >62 years with chronic diseases, and retired people were most affected. Furthermore, the influenza vaccine could decrease the severeness of COVID-19 cases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunas contra la Influenza / COVID-19 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Mexico Idioma: En Revista: Front Public Health Año: 2021 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunas contra la Influenza / COVID-19 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Mexico Idioma: En Revista: Front Public Health Año: 2021 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza