Modeling human tumor-immune environments in vivo for the preclinical assessment of immunotherapies.

Bareham, Bethany; Georgakopoulos, Nikitas; Matas-Céspedes, Alba; Curran, Michelle; Saeb-Parsy, Kourosh

Bareham, Bethany; Georgakopoulos, Nikitas; Matas-Céspedes, Alba; Curran, Michelle; Saeb-Parsy, Kourosh.

Afiliación

Bareham B; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Campus, Cambridge, UK.
Georgakopoulos N; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Campus, Cambridge, UK.
Matas-Céspedes A; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Campus, Cambridge, UK.
Curran M; Clinical Pharmacology and Safety Sciences, AstraZeneca, BioPharmaceuticals R&D, Cambridge, UK.
Saeb-Parsy K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Campus, Cambridge, UK.

Cancer Immunol Immunother ; 70(10): 2737-2750, 2021 Oct.

Article en En | MEDLINE | ID: mdl-33830275

Asunto(s)

Inmunoterapia/métodos; Microambiente Tumoral/inmunología; Animales; Modelos Animales de Enfermedad; Humanos; Ratones; Medición de Riesgo

Palabras clave

Animal models; Autologous models; Cancer; Immune-system; Immunotherapies; Preclinical Safety-assessment/risk management

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microambiente Tumoral / Inmunoterapia Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Alemania

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