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Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer's Disease Mouse Model.
He, Feng; Chou, C James; Scheiner, Matthias; Poeta, Eleonora; Yuan Chen, Natalia; Gunesch, Sandra; Hoffmann, Matthias; Sotriffer, Christoph; Monti, Barbara; Maurice, Tangui; Decker, Michael.
Afiliación
  • He F; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
  • Chou CJ; Department of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, United States.
  • Scheiner M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
  • Poeta E; Department of Pharmacy and Biotechnologies, University of Bologna, Via Selmi 3, Bologna 40126, Italy.
  • Yuan Chen N; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
  • Gunesch S; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
  • Hoffmann M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
  • Sotriffer C; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
  • Monti B; Department of Pharmacy and Biotechnologies, University of Bologna, Via Selmi 3, Bologna 40126, Italy.
  • Maurice T; MMDN, Univ Montpellier, EPHE, INSERM, Montpellier 34095, France.
  • Decker M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.
J Med Chem ; 64(7): 3794-3812, 2021 04 08.
Article en En | MEDLINE | ID: mdl-33769811
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triptaminas / Fármacos Neuroprotectores / Ácidos Cumáricos / Enfermedad de Alzheimer / Histona Desacetilasa 6 / Factores Inmunológicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triptaminas / Fármacos Neuroprotectores / Ácidos Cumáricos / Enfermedad de Alzheimer / Histona Desacetilasa 6 / Factores Inmunológicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos