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Acute renal infarction: long-term renal outcome and prognostic factors.
Delezire, Arnaud; Terrasse, Marianne; Bouet, Julien; Laot, Maxence; Brun, Vanessa; Oger, Emmanuel; Vigneau, Cécile.
Afiliación
  • Delezire A; Service de Néphrologie, CHU Hôpital Pontchaillou, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France. arnaud.delezire@hotmail.fr.
  • Terrasse M; Service de Néphrologie, CHU Hôpital Pontchaillou, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France.
  • Bouet J; Centre Hospitalier Public du Cotentin, Service de Néphrologie, Rue Trottebec, BP 208, 50102, Cherbourg Octeville Cedex, France.
  • Laot M; CHU Hôpital Pontchaillou, Service d'Imagerie médicale, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France.
  • Brun V; CHU Hôpital Pontchaillou, Service d'Imagerie médicale, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France.
  • Oger E; Faculté de Médecine, Université Rennes 1, Équipe de Pharmacoépidémiologie, INSERM CIC 0203, 2 avenue du Professeur Léon Bernard, CS 34317, 35043, Rennes Cedex, France.
  • Vigneau C; Centre Régional de Pharmacovigilance, CHU Hôpital Pontchaillou, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France.
J Nephrol ; 34(5): 1501-1509, 2021 10.
Article en En | MEDLINE | ID: mdl-33765299
INTRODUCTION: Acute renal infarction is a rare occurence, whose  prognosis and long-term outcomes remain poorly studied. This study evaluated whether clinical and radiological features at diagnosis can be associated with the long-term outcomes (blood pressure, kidney function and mortality). METHODS: We retrospectively analyzed the demographic, clinical, biological and radiological data of patients with acute renal infarction hospitalized at Rennes University Hospital between 1997 and 2017 (n = 94). RESULTS: Patients were followed-up for a median of 60 months. At time of diagnosis of acute renal infarction median age was 53 years, 45% of the patients had acute hypertension, and 31% had Acute Kidney Injury (AKI) requiring dialysis in seven patients. The median Lactate DeHydrogenase (LDH) level was 977 IU/mL. The median extent of kidney damage was 14%, with left renal involvement in 51% of patients. At 60 months of follow-up, 66% of patients had developed Chronic Kidney Disease (CKD) stage 3 or higher, and 55% had hypertension since diagnosis. Age, acute development of hypertension and AKI at diagnosis were associated with long-term CKD (stage 3 or higher) in multivariate analyses, but the extent of kidney damage was not. During the follow-up, 21% of patients died, and only age resulted as a predisposing factor. No tested factor was correlated with long-term hypertension. DISCUSSION: Age, acute development of hypertension, and AKI were correlated with long term CKD, whereas no factor was correlated with long-term hypertension after acute renal infarction.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Lesión Renal Aguda Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Middle aged Idioma: En Revista: J Nephrol Asunto de la revista: NEFROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Lesión Renal Aguda Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Middle aged Idioma: En Revista: J Nephrol Asunto de la revista: NEFROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Italia