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A wearable patch for continuous analysis of thermoregulatory sweat at rest.
Nyein, Hnin Yin Yin; Bariya, Mallika; Tran, Brandon; Ahn, Christine Heera; Brown, Brenden Janatpour; Ji, Wenbo; Davis, Noelle; Javey, Ali.
Afiliación
  • Nyein HYY; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.
  • Bariya M; Berkeley Sensor and Actuator Center, University of California, Berkeley, CA, USA.
  • Tran B; Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Ahn CH; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.
  • Brown BJ; Berkeley Sensor and Actuator Center, University of California, Berkeley, CA, USA.
  • Ji W; Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Davis N; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.
  • Javey A; Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Nat Commun ; 12(1): 1823, 2021 03 23.
Article en En | MEDLINE | ID: mdl-33758197
The body naturally and continuously secretes sweat for thermoregulation during sedentary and routine activities at rates that can reflect underlying health conditions, including nerve damage, autonomic and metabolic disorders, and chronic stress. However, low secretion rates and evaporation pose challenges for collecting resting thermoregulatory sweat for non-invasive analysis of body physiology. Here we present wearable patches for continuous sweat monitoring at rest, using microfluidics to combat evaporation and enable selective monitoring of secretion rate. We integrate hydrophilic fillers for rapid sweat uptake into the sensing channel, reducing required sweat accumulation time towards real-time measurement. Along with sweat rate sensors, we integrate electrochemical sensors for pH, Cl-, and levodopa monitoring. We demonstrate patch functionality for dynamic sweat analysis related to routine activities, stress events, hypoglycemia-induced sweating, and Parkinson's disease. By enabling sweat analysis compatible with sedentary, routine, and daily activities, these patches enable continuous, autonomous monitoring of body physiology at rest.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sudor / Sudoración / Regulación de la Temperatura Corporal / Técnicas Biosensibles / Microfluídica / Dispositivos Electrónicos Vestibles Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sudor / Sudoración / Regulación de la Temperatura Corporal / Técnicas Biosensibles / Microfluídica / Dispositivos Electrónicos Vestibles Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido