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Research progress on two-component signal transduction systems in Porphyromonas gingivalis.
Yao, Ke; Cai, Jing-Yi; Zhao, Lei; Wu, Ya-Fei; Zhao, Zhi-He; Shen, Dao-Nan.
Afiliación
  • Yao K; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
  • Cai JY; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
  • Zhao L; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
  • Wu YF; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
  • Zhao ZH; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
  • Shen DN; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 39(1): 88-93, 2021 Feb 01.
Article en En, Zh | MEDLINE | ID: mdl-33723942
Porphyromonas gingivalis (P. gingivalis), a Gram-negative oral anaerobe, is considered to be a major pathogenic agent involved in the onset and progression of chronic periodontitis. P. gingivalis must be able to perceive and respond to the complicated changes in host to survive the environmental challenges, in which the two-component signal transduction systems (TCSs) play critical roles by connecting input signals to cellular physiological output. Canonical TCS consists of a sensor histidine kinase and a cognate response regulator that functions via a phosphorylation cascade. In this review, the roles of TCSs in P. gingivalis were demonstrated by illustrating the target genes and modulation modes, which may help elucidate the underlying mechanisms in future studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Porphyromonas gingivalis Idioma: En / Zh Revista: Hua Xi Kou Qiang Yi Xue Za Zhi Asunto de la revista: ODONTOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Porphyromonas gingivalis Idioma: En / Zh Revista: Hua Xi Kou Qiang Yi Xue Za Zhi Asunto de la revista: ODONTOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: China