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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
Sivák, Ladislav; Subr, Vladimír; Kovárová, Jirina; Dvoráková, Barbora; Sírová, Milada; Ríhová, Blanka; Randárová, Eva; Kraus, Michal; Tomala, Jakub; Studenovský, Martin; Vondrácková, Michaela; Sedlácek, Radislav; Makovický, Petr; Fucíková, Jitka; Vosáhlíková, Sárka; Spísek, Radek; Kostka, Libor; Etrych, Tomás; Kovár, Marek.
Afiliación
  • Sivák L; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Subr V; Institute of Macromolecular Chemistry, Czech Academy of Sciences, v.v.i., Heyrovskeho nam. 2, 16206 Prague, Czech Republic.
  • Kovárová J; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Dvoráková B; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Sírová M; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Ríhová B; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Randárová E; Institute of Macromolecular Chemistry, Czech Academy of Sciences, v.v.i., Heyrovskeho nam. 2, 16206 Prague, Czech Republic.
  • Kraus M; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Tomala J; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Studenovský M; Institute of Macromolecular Chemistry, Czech Academy of Sciences, v.v.i., Heyrovskeho nam. 2, 16206 Prague, Czech Republic.
  • Vondrácková M; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic.
  • Sedlácek R; Czech Center of Phenogenomics, Institute of Molecular Genetics, Czech Academy of Sciences, v.v.i., Prumyslova 595, 25250 Vestec, Czech Republic.
  • Makovický P; Czech Center of Phenogenomics, Institute of Molecular Genetics, Czech Academy of Sciences, v.v.i., Prumyslova 595, 25250 Vestec, Czech Republic.
  • Fucíková J; Department of Immunology, Charles University, 2(nd) Faculty of Medicine and University Hospital Motol, V uvalu 84, 15006 Prague, Czech Republic; Sotio, Jankovcova 1518, 17000 Prague, Czech Republic.
  • Vosáhlíková S; Sotio, Jankovcova 1518, 17000 Prague, Czech Republic.
  • Spísek R; Department of Immunology, Charles University, 2(nd) Faculty of Medicine and University Hospital Motol, V uvalu 84, 15006 Prague, Czech Republic; Sotio, Jankovcova 1518, 17000 Prague, Czech Republic.
  • Kostka L; Institute of Macromolecular Chemistry, Czech Academy of Sciences, v.v.i., Heyrovskeho nam. 2, 16206 Prague, Czech Republic.
  • Etrych T; Institute of Macromolecular Chemistry, Czech Academy of Sciences, v.v.i., Heyrovskeho nam. 2, 16206 Prague, Czech Republic. Electronic address: etrych@imc.cas.cz.
  • Kovár M; Institute of Microbiology, Czech Academy of Sciences, v.v.i., Videnska 1083, 14220 Prague, Czech Republic. Electronic address: makovar@biomed.cas.cz.
J Control Release ; 332: 563-580, 2021 04 10.
Article en En | MEDLINE | ID: mdl-33722611
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polímeros / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polímeros / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Países Bajos