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Angiomatoid fibrosis histiocytoma in the pulmonary artery: A case report.
Mishima, Shuji; Mishima, Osamu; Azuhata, Koji; Shimojo, Hisashi; Ito, Nobuo; Misawa, Kenji; Shimizu, Kimihiro.
Afiliación
  • Mishima S; Department of General Surgery, Aizawa Hospital, Matsumoto, Japan.
  • Mishima O; Department of General Surgery, Aizawa Hospital, Matsumoto, Japan.
  • Azuhata K; Department of Anatomic Pathology, Aizawa Hospital, Matsumoto, Japan.
  • Shimojo H; Department of Anatomic Pathology, Aizawa Hospital, Matsumoto, Japan.
  • Ito N; Department of Anatomic Pathology, Aizawa Hospital, Matsumoto, Japan.
  • Misawa K; Department of General Surgery, Aizawa Hospital, Matsumoto, Japan.
  • Shimizu K; Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Thorac Cancer ; 12(9): 1453-1456, 2021 05.
Article en En | MEDLINE | ID: mdl-33713576
Angiomatoid fibrosis histiocytoma (AFH) is a rare neoplastic disease. Only one report has demonstrated an intraluminal tumor of the pulmonary artery (PA) corresponding to AFH to date. We describe the case of AFH with EWSR1-CREB1 fusion occurring in the ascending artery. A 42-year-old man exhibited an abnormal nodule on chest computed tomography (CT) during checkup. It revealed an intraluminal mass in the ascending artery with significant metabolic uptake in positron emission tomography (PET)/CT. Therefore, right upper lobectomy with wedge resection of the PA trunk was performed. Histologically, the tumor was multinodular and surrounded by a dense lymphoplasmacytic cuff. Each nodule was composed of myxoid stroma and comprised ovoid or spindle cell fascicles with mild atypia. Fluorescent in situ hybridization (FISH) analysis confirmed EWSR1-CREB1 fusion. A diagnosed as AFH was made. This report widens the spectrum of differential diagnoses of primary tumors occurring in the PA.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteria Pulmonar / Histiocitoma Límite: Adult / Humans / Male Idioma: En Revista: Thorac Cancer Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Singapur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteria Pulmonar / Histiocitoma Límite: Adult / Humans / Male Idioma: En Revista: Thorac Cancer Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Singapur