Enhanced production of clavulanic acid by improving glycerol utilization using reporter-guided mutagenesis of an industrial Streptomyces clavuligerus strain.

Shin, Chang-Hun; Cho, Hang Su; Won, Hyung-Jin; Kwon, Ho Jeong; Kim, Chan-Wha; Yoon, Yeo Joon

Shin, Chang-Hun; Cho, Hang Su; Won, Hyung-Jin; Kwon, Ho Jeong; Kim, Chan-Wha; Yoon, Yeo Joon.

Afiliación

Shin CH; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Cho HS; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.
Won HJ; Fermentation Technology Team, Research Institute of CKD Bio, Ansan 15604, Republic of Korea.
Kwon HJ; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.
Kim CW; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Yoon YJ; Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.

J Ind Microbiol Biotechnol ; 48(3-4)2021 Jun 04.

Article en En | MEDLINE | ID: mdl-33693777

Asunto(s)

Ácido Clavulánico/biosíntesis; Glicerol/metabolismo; Streptomyces/metabolismo; Reactores Biológicos; Mutagénesis; Operón; Streptomyces/genética

Palabras clave

Streptomyces clavuligerus; Clavulanic acid; Glycerol utilization; Reporter-guided selection

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Streptomyces / Ácido Clavulánico / Glicerol Idioma: En Revista: J Ind Microbiol Biotechnol Asunto de la revista: BIOTECNOLOGIA / MICROBIOLOGIA Año: 2021 Tipo del documento: Article Pais de publicación: Alemania

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google