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Use of catheter with 2-methacryloyloxyethyl phosphorylcholine polymer coating is associated with long-term availability of central venous port.
Iida, Yuuki; Hongo, Kumiko; Onoda, Takanobu; Kita, Yusuke; Ishihara, Yukio; Takabayashi, Naoki; Kobayashi, Ryo; Hiramatsu, Takeyuki.
Afiliación
  • Iida Y; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan. yiida-tky@umin.ac.jp.
  • Hongo K; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
  • Onoda T; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
  • Kita Y; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
  • Ishihara Y; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
  • Takabayashi N; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
  • Kobayashi R; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
  • Hiramatsu T; Department of Surgery, Yaizu City Hospital, 1000 Dobara, Yaizu City, Shizuoka, 425-8505, Japan.
Sci Rep ; 11(1): 5385, 2021 03 08.
Article en En | MEDLINE | ID: mdl-33686152
Central venous port (CVP) is a widely used totally implantable venous access device. Recognition of risks associated with CVP-related complications is clinically important for safe, reliable, and long-term intravenous access. We therefore investigated factors associated with CVP infection and evulsion, including the device type. A total of 308 consecutive patients with initial CVP implantation between January 2011 and December 2017 were retrospectively reviewed, and the association of clinical features with CVP-related complications were analyzed. Intraoperative and postoperative complications occurred in 11 (3.6%) and 39 (12.7%) patients, respectively. The overall rate of CVP availability at six months was 91.4%. Malignancy and 2-Methacryloyloxyethyl phosphorylcholine (MPC) polymer-coated catheter use were negatively associated with the incidence of CVP infections. Accordingly, malignancy and MPC polymer-coated catheter use were independent predictors for lower CVP evulsion rate (odds ratio, 0.23 and 0.18, respectively). Furthermore, both factors were significantly associated with longer CVP availability (hazard ratio, 0.24 and 0.27, respectively). This retrospective study identified factors associated with CVP-related complications and long-term CVP availability. Notably, MPC polymer-coated catheter use was significantly associated with a lower rate of CVP infection and longer CVP availability, suggesting the preventive effect of MPC coating on CVP infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosforilcolina / Cateterismo Venoso Central / Infecciones Relacionadas con Catéteres / Catéteres Venosos Centrales / Metacrilatos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosforilcolina / Cateterismo Venoso Central / Infecciones Relacionadas con Catéteres / Catéteres Venosos Centrales / Metacrilatos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido