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Outcomes of COVID-19 With the Mayo Clinic Model of Care and Research.
O'Horo, John Charles; Cerhan, James R; Cahn, Elliot J; Bauer, Philippe R; Temesgen, Zelalem; Ebbert, Jon; Abril, Andy; Abu Saleh, Omar M; Assi, Mariam; Berbari, Elie F; Bierle, Dennis M; Bosch, Wendelyn; Burger, Charles D; Cano Cevallos, Edison J; Clements, Casey M; Carmona Porquera, Eva M; Castillo Almeida, Natalia E; Challener, Douglas W; Chesdachai, Supavit; Comba, Isin Y; Corsini Campioli, Cristina G; Crane, Sarah J; Dababneh, Ala S; Enzler, Mark J; Fadel, Hind J; Ganesh, Ravindra; De Moraes, Alice Gallo; Go, John R; Gordon, Joel E; Gurram, Pooja R; Guru, Pramod K; Halverson, Erika L; Harrison, Michael F; Heaton, Heather A; Hurt, Ryan; Kasten, Mary J; Lee, Augustine S; Levy, Emily R; Libertin, Claudia R; Mallea, Jorge M; Marshall, William F; Matcha, Gautam; Meehan, Anne M; Franco, Pablo Moreno; Morice, William G; O'Brien, Jennifer J; Oeckler, Richard; Ommen, Steve; Oravec, Caitlin P; Orenstein, Robert.
Afiliación
  • O'Horo JC; Division of Infectious Diseases, Mayo Clinic, Rochester, MN; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
  • Cerhan JR; Division of Health Science Research, Mayo Clinic, Rochester, MN.
  • Cahn EJ; Division of Health Science Research, Mayo Clinic, Rochester, MN.
  • Bauer PR; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
  • Temesgen Z; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Ebbert J; Division of Community Internal Medicine, Mayo Clinic, Rochester, MN.
  • Abril A; Division of Rheumatology, Mayo Clinic, Jacksonville, FL.
  • Abu Saleh OM; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Assi M; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Berbari EF; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Bierle DM; Division of General Internal Medicine, Mayo Clinic, Rochester, MN.
  • Bosch W; Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL.
  • Burger CD; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville, FL.
  • Cano Cevallos EJ; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Clements CM; Department of Emergency Medicine, Mayo Clinic, Rochester, MN.
  • Carmona Porquera EM; Division of Infectious Diseases, Mayo Clinic, Rochester, MN; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
  • Castillo Almeida NE; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Challener DW; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Chesdachai S; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Comba IY; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Corsini Campioli CG; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Crane SJ; Division of Community Internal Medicine, Mayo Clinic, Rochester, MN.
  • Dababneh AS; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Enzler MJ; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Fadel HJ; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Ganesh R; Division of General Internal Medicine, Mayo Clinic, Rochester, MN.
  • De Moraes AG; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
  • Go JR; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Gordon JE; Department of Family Medicine, Mayo Clinic Health System, Mankato, MN.
  • Gurram PR; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Guru PK; Department of Critical Care Medicine, Mayo Clinic, Jacksonville, FL.
  • Halverson EL; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Harrison MF; Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL.
  • Heaton HA; Department of Emergency Medicine, Mayo Clinic, Rochester, MN.
  • Hurt R; Division of General Internal Medicine, Mayo Clinic, Rochester, MN.
  • Kasten MJ; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Lee AS; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville, FL.
  • Levy ER; Division of Pediatric Critical Care Medicine, Mayo Clinic, Rochester, MN; Division of Pediatric Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Libertin CR; Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL.
  • Mallea JM; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville, FL.
  • Marshall WF; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Matcha G; Department of Internal Medicine, Mayo Clinic, Jacksonville, FL.
  • Meehan AM; Division of Hospital Medicine, Mayo Clinic, Rochester, MN.
  • Franco PM; Department of Critical Care Medicine, Mayo Clinic, Jacksonville, FL.
  • Morice WG; Department of Laboratory Medicine Pathology, Mayo Clinic, Rochester, MN.
  • O'Brien JJ; Department of Laboratory Medicine Pathology, Mayo Clinic, Jacksonville, FL.
  • Oeckler R; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN; Division of Infectious Diseases, Mayo Clinic, Scottsdale, AZ.
  • Ommen S; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN.
  • Oravec CP; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
  • Orenstein R; Division of Infectious Diseases, Mayo Clinic, Rochester, MN.
Mayo Clin Proc ; 96(3): 601-618, 2021 03.
Article en En | MEDLINE | ID: mdl-33673913
OBJECTIVE: To report the Mayo Clinic experience with coronavirus disease 2019 (COVID-19) related to patient outcomes. METHODS: We conducted a retrospective chart review of patients with COVID-19 diagnosed between March 1, 2020, and July 31, 2020, at any of the Mayo Clinic sites. We abstracted pertinent comorbid conditions such as age, sex, body mass index, Charlson Comorbidity Index variables, and treatments received. Factors associated with hospitalization and mortality were assessed in univariate and multivariate models. RESULTS: A total of 7891 patients with confirmed COVID-19 infection with research authorization on file received care across the Mayo Clinic sites during the study period. Of these, 7217 patients were adults 18 years or older who were analyzed further. A total of 897 (11.4%) patients required hospitalization, and 354 (4.9%) received care in the intensive care unit (ICU). All hospitalized patients were reviewed by a COVID-19 Treatment Review Panel, and 77.5% (695 of 897) of inpatients received a COVID-19-directed therapy. Overall mortality was 1.2% (94 of 7891), with 7.1% (64 of 897) mortality in hospitalized patients and 11.3% (40 of 354) in patients requiring ICU care. CONCLUSION: Mayo Clinic outcomes of patients with COVID-19 infection in the ICU, hospital, and community compare favorably with those reported nationally. This likely reflects the impact of interprofessional multidisciplinary team evaluation, effective leveraging of clinical trials and available treatments, deployment of remote monitoring tools, and maintenance of adequate operating capacity to not require surge adjustments. These best practices can help guide other health care systems with the continuing response to the COVID-19 pandemic.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Investigación Biomédica / Pandemias / SARS-CoV-2 / COVID-19 Tipo de estudio: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Mayo Clin Proc Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Investigación Biomédica / Pandemias / SARS-CoV-2 / COVID-19 Tipo de estudio: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Mayo Clin Proc Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido