Copper Dependent Modulation of &#945;-Synuclein Phosphorylation in Differentiated SHSY5Y Neuroblastoma Cells.

Greco, Marco; Spinelli, Chiara Carmela; De Riccardis, Lidia; Buccolieri, Alessandro; Di Giulio, Simona; Musarò, Debora; Pagano, Claudia; Manno, Daniela; Maffia, Michele

Copper Dependent Modulation of α-Synuclein Phosphorylation in Differentiated SHSY5Y Neuroblastoma Cells.

Greco, Marco; Spinelli, Chiara Carmela; De Riccardis, Lidia; Buccolieri, Alessandro; Di Giulio, Simona; Musarò, Debora; Pagano, Claudia; Manno, Daniela; Maffia, Michele.

Afiliación

Greco M; Department of Mathematics and Physics "E. De Giorgi", University of Salento, 73100 Lecce, Italy.
Spinelli CC; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
De Riccardis L; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Buccolieri A; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Di Giulio S; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Musarò D; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Pagano C; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Manno D; Department of Mathematics and Physics "E. De Giorgi", University of Salento, 73100 Lecce, Italy.
Maffia M; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.

Int J Mol Sci ; 22(4)2021 Feb 18.

Article en En | MEDLINE | ID: mdl-33670800

Asunto(s)

Cobre/metabolismo; Neuroblastoma/metabolismo; Neuroblastoma/patología; alfa-Sinucleína/metabolismo; Diferenciación Celular/efectos de los fármacos; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Cobre/farmacología; Proteínas Transportadoras de Cobre/genética; Proteínas Transportadoras de Cobre/metabolismo; ATPasas Transportadoras de Cobre/genética; ATPasas Transportadoras de Cobre/metabolismo; Humanos; Chaperonas Moleculares/genética; Chaperonas Moleculares/metabolismo; Fosforilación/efectos de los fármacos; Proteínas Serina-Treonina Quinasas/genética; Proteínas Serina-Treonina Quinasas/metabolismo

Palabras clave

Parkinson's disease (PD); ROS; copper; oxidative stress; α-synuclein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cobre / Alfa-Sinucleína / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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