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Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL).
Shaw, Timothy I; Dong, Li; Tian, Liqing; Qian, Chenxi; Liu, Yu; Ju, Bensheng; High, Anthony; Kavdia, Kanisha; Pagala, Vishwajeeth R; Shaner, Bridget; Pei, Deqing; Easton, John; Janke, Laura J; Porter, Shaina N; Ma, Xiaotu; Cheng, Cheng; Pruett-Miller, Shondra M; Choi, John; Yu, Jiyang; Peng, Junmin; Gu, Wei; Look, A Thomas; Downing, James R; Zhang, Jinghui.
Afiliación
  • Shaw TI; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Dong L; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Tian L; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Qian C; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Liu Y; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Ju B; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • High A; Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, USA.
  • Kavdia K; Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, USA.
  • Pagala VR; Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, USA.
  • Shaner B; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Pei D; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, USA.
  • Easton J; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Janke LJ; Department of Pathology, St Jude Children's Research Hospital, Memphis, USA.
  • Porter SN; Department of Cell and Molecular Biology, St Jude Children's Research Hospital, Memphis, USA.
  • Ma X; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Cheng C; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, USA.
  • Pruett-Miller SM; Department of Cell and Molecular Biology, St Jude Children's Research Hospital, Memphis, USA.
  • Choi J; Department of Pathology, St Jude Children's Research Hospital, Memphis, USA.
  • Yu J; Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS321, Memphis, TN, 38105, USA.
  • Peng J; Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, USA.
  • Gu W; Departments of Structural Biology and Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, USA.
  • Look AT; Department of Pathology and Cell Biology and Institute for Cancer Genetics, Columbia University, New York, USA.
  • Downing JR; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02216, USA.
  • Zhang J; Department of Pathology, St Jude Children's Research Hospital, Memphis, USA.
Sci Rep ; 11(1): 5154, 2021 03 04.
Article en En | MEDLINE | ID: mdl-33664368
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Peptidasa Específica de Ubiquitina 7 / Proteína 1 de la Leucemia Linfocítica T Aguda Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Peptidasa Específica de Ubiquitina 7 / Proteína 1 de la Leucemia Linfocítica T Aguda Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido