Your browser doesn't support javascript.
loading
Clinical characteristics and outcome of patients aged over 80 years with covid-19.
Capdevila-Reniu, Aina; Pellice, Martina; Prieto-González, Sergio; Ventosa, Helena; Ladino, Andrea; Naval, Jose; Rodriguez-Nuñez, Olga; César Milisenda, Jose; Moreno-Lozano, Pedro Juan; Soriano, Alex; Bosch, Xavier; López-Soto, Alfonso.
Afiliación
  • Capdevila-Reniu A; Department of Internal Medicine.
  • Pellice M; Department of Internal Medicine.
  • Prieto-González S; Department of Internal Medicine.
  • Ventosa H; Department of Internal Medicine.
  • Ladino A; Department of Internal Medicine.
  • Naval J; Department of Internal Medicine.
  • Rodriguez-Nuñez O; Department of Internal Medicine.
  • César Milisenda J; Department of Internal Medicine.
  • Moreno-Lozano PJ; Department of Internal Medicine.
  • Soriano A; Department of Infectious Diseases, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Spain.
  • Bosch X; Department of Internal Medicine.
  • López-Soto A; Department of Internal Medicine.
Medicine (Baltimore) ; 100(8): e24750, 2021 Feb 26.
Article en En | MEDLINE | ID: mdl-33663089
ABSTRACT: To investigate the clinical characteristics and outcome of octogenarians with covid-19.This is a observational, retrospective, descriptive study.Consecutive patients aged >80 years who were admitted for covid-19 pneumonia during a 6 weeks period (March 20-April 30, 2020).Illness severity on admission was classified according to World Health Organization (WHO) criteria: mild, moderate, severe, and critical. Data collected included demographics, presenting symptoms, radiological and laboratory findings, comorbidities, functional status, treatment, and clinical outcome.There were 159 patients (52.2% women) with a median age of 85.99 (IQR: 80-98). The median Barthel index was 90 (40-100) and Charlson index was 5 (5-6). Most common presenting symptoms were fever, dyspnea, and cough. Patients had mild (8.2%), moderate (52.2%), or severe (39.6%) illness according to WHO criteria. A bilateral pulmonary involvement was seen in 86% of patients. Laboratory analysis revealed increased serum concentrations of inflammatory parameters (C-reactive protein, ferritin, lactate dehydrogenase, and D-dimer) with an abnormal lymphocyte count [0.88 × 109/L (0.5)]. Treatments included corticosteroids in 37%, and biological therapies in 17.6%. Fifty three (33.3%) patients died during hospitalization, with a median time from admission to death of 3 (IQR 1-6) days. Mortality was higher in men (55%). Deceased patients had a significantly higher frequency of dyspnea, increased inflammatory parameters, and illness severity compared to survivors.One-third of octogenarians with covid-19 died during hospitalization and most had bilateral lung involvement. A further knowledge of the characteristics and outcome of this population may assist clinicians in the decision-making process in these patients.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Observational_studies / Prognostic_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Medicine (Baltimore) Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Observational_studies / Prognostic_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Medicine (Baltimore) Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos