Kidney Mesenchymal Stem Cell-derived Extracellular Vesicles Engineered to Express Erythropoietin Improve Renal Anemia in Mice with Chronic Kidney Disease.

Choi, Hoon Young; Kim, Tae Yeon; Lee, Mirae; Kim, Soo Hyun; Jhee, Jong Hyun; Lee, Yong Kyu; Kim, Hyung Jong; Park, Hyeong Cheon

Choi, Hoon Young; Kim, Tae Yeon; Lee, Mirae; Kim, Soo Hyun; Jhee, Jong Hyun; Lee, Yong Kyu; Kim, Hyung Jong; Park, Hyeong Cheon.

Afiliación

Choi HY; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, the Republic of Korea.
Kim TY; Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, the Republic of Korea.
Lee M; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, the Republic of Korea.
Kim SH; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, the Republic of Korea.
Jhee JH; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, the Republic of Korea.
Lee YK; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, the Republic of Korea.
Kim HJ; Department of Internal Medicine, Nephrology Division, NHIS Ilsan Hospital, Goyang, the Republic of Korea.
Park HC; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, the Republic of Korea.

Stem Cell Rev Rep ; 18(3): 980-992, 2022 03.

Article en En | MEDLINE | ID: mdl-33651336

Asunto(s)

Anemia; Eritropoyetina; Vesículas Extracelulares; Células Madre Mesenquimatosas; Insuficiencia Renal Crónica; Anemia/terapia; Animales; Creatinina; Eritropoyetina/genética; Eritropoyetina/farmacología; Femenino; Humanos; Riñón/fisiología; Masculino; Ratones; ARN Mensajero/genética; Insuficiencia Renal Crónica/terapia

Palabras clave

Chronic kidney disease; Erythropoietin; Extracellular vesicles; Kidney mesenchymal stem cells; Renal anemia; mRNA transfer

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eritropoyetina / Insuficiencia Renal Crónica / Células Madre Mesenquimatosas / Vesículas Extracelulares / Anemia Límite: Animals / Female / Humans / Male Idioma: En Revista: Stem Cell Rev Rep Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

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