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Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Velten, Lars; Story, Benjamin A; Hernández-Malmierca, Pablo; Raffel, Simon; Leonce, Daniel R; Milbank, Jennifer; Paulsen, Malte; Demir, Aykut; Szu-Tu, Chelsea; Frömel, Robert; Lutz, Christoph; Nowak, Daniel; Jann, Johann-Christoph; Pabst, Caroline; Boch, Tobias; Hofmann, Wolf-Karsten; Müller-Tidow, Carsten; Trumpp, Andreas; Haas, Simon; Steinmetz, Lars M.
Afiliación
  • Velten L; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. lars.velten@crg.eu.
  • Story BA; Universitat Pompeu Fabra (UPF), Barcelona, Spain. lars.velten@crg.eu.
  • Hernández-Malmierca P; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Raffel S; Swiss Federal Institute of Technology (ETH) Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
  • Leonce DR; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.
  • Milbank J; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.
  • Paulsen M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.
  • Demir A; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.
  • Szu-Tu C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
  • Frömel R; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Lutz C; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Nowak D; European Molecular Biology Laboratory (EMBL), Flow Cytometry Core Facility, Heidelberg, Germany.
  • Jann JC; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
  • Pabst C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Boch T; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Hofmann WK; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Müller-Tidow C; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
  • Trumpp A; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
  • Haas S; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Steinmetz LM; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Nat Commun ; 12(1): 1366, 2021 03 01.
Article en En | MEDLINE | ID: mdl-33649320

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Leucemia Mieloide Aguda / Células Clonales / Análisis de la Célula Individual / Transcriptoma Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Leucemia Mieloide Aguda / Células Clonales / Análisis de la Célula Individual / Transcriptoma Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido