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Clinical and radiological assessment of the induced membrane technique using beta-tricalcium phosphate in reconstructive surgery for lower extremity long bone defects.
Sasaki, Gen; Watanabe, Yoshinobu; Yasui, Youichi; Nishizawa, Mari; Saka, Natsumi; Kawano, Hirotaka; Miyamoto, Wataru.
Afiliación
  • Sasaki G; Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
  • Watanabe Y; Trauma and Reconstruction Center, Teikyo University Hospital, Tokyo, Japan.
  • Yasui Y; Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
  • Nishizawa M; Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
  • Saka N; Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
  • Kawano H; Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
  • Miyamoto W; Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Bone Joint J ; 103-B(3): 456-461, 2021 Mar.
Article en En | MEDLINE | ID: mdl-33641428
AIMS: To clarify the effectiveness of the induced membrane technique (IMT) using beta-tricalcium phosphate (ß-TCP) for reconstruction of segmental bone defects by evaluating clinical and radiological outcomes, and the effect of defect size and operated site on surgical outcomes. METHODS: A review of the medical records was conducted of consecutive 35 lower limbs (30 males and five females; median age 46 years (interquartile range (IQR) 40 to 61)) treated with IMT using ß-TCP between 2014 and 2018. Lower Extremity Functional Score (LEFS) was examined preoperatively and at final follow-up to clarify patient-centered outcomes. Bone healing was assessed radiologically, and time from the second stage to bone healing was also evaluated. Patients were divided into ≥ 50 mm and < 50 mm defect groups and into femoral reconstruction, tibial reconstruction, and ankle arthrodesis groups. RESULTS: There were ten and 25 defects in the femur and tibia, respectively. Median LEFS improved significantly from 8 (IQR 1.5 to 19.3) preoperatively to 63.5 (IQR 57 to 73.3) at final follow-up (p < 0.001). Bone healing was achieved in all limbs, and median time from the second stage to bone healing was six months (IQR 5 to 10). Median time to bone healing, preoperative LEFS, or postoperative LEFS did not differ significantly between the defect size groups or among the treatment groups. CONCLUSION: IMT using ß-TCP provided satisfactory clinical and radiological outcomes for segmental bone defects in the lower limbs; surgical outcomes were not influenced by bone defect size or operated part. Cite this article: Bone Joint J 2021;103-B(3):456-461.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tibia / Fosfatos de Calcio / Trasplante Óseo / Procedimientos de Cirugía Plástica / Fémur / Ilion Tipo de estudio: Observational_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Bone Joint J Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tibia / Fosfatos de Calcio / Trasplante Óseo / Procedimientos de Cirugía Plástica / Fémur / Ilion Tipo de estudio: Observational_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Bone Joint J Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido