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Potentiating CD8+ T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling.
Yuan, Juanjuan; Cai, Ting; Zheng, Xiaojun; Ren, Yangzi; Qi, Jingwen; Lu, Xiaofei; Chen, Huihui; Lin, Huizhen; Chen, Zijie; Liu, Mengnan; He, Shangwen; Chen, Qijun; Feng, Siyang; Wu, Yingjun; Zhang, Zhenhai; Ding, Yanqing; Yang, Wei.
Afiliación
  • Yuan J; Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, 528308, China.
  • Cai T; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zheng X; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China.
  • Ren Y; Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, 528308, China.
  • Qi J; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Lu X; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China.
  • Chen H; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Lin H; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Chen Z; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China.
  • Liu M; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • He S; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Chen Q; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Feng S; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China.
  • Wu Y; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhang Z; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China.
  • Ding Y; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Yang W; Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China.
Protein Cell ; 12(4): 240-260, 2021 04.
Article en En | MEDLINE | ID: mdl-33606190
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de LDL / Receptores de Antígenos de Linfocitos T / Transducción de Señal / Linfocitos T CD8-positivos / Proproteína Convertasa 9 / Inmunidad Celular / Neoplasias Límite: Animals / Humans Idioma: En Revista: Protein Cell Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de LDL / Receptores de Antígenos de Linfocitos T / Transducción de Señal / Linfocitos T CD8-positivos / Proproteína Convertasa 9 / Inmunidad Celular / Neoplasias Límite: Animals / Humans Idioma: En Revista: Protein Cell Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania