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Oral antibiotic bowel decontamination in open and laparoscopic sigmoid resections for diverticular disease.
Wirth, Ulrich; Schardey, Josefine; von Ahnen, Thomas; Zimmermann, Petra; Kühn, Florian; Werner, Jens; Schardey, Hans Martin; Rau, Bettina M; Gumpp, Julia.
Afiliación
  • Wirth U; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany. Ulrich.Wirth@med.uni-muenchen.de.
  • Schardey J; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
  • von Ahnen T; Department of General, Visceral, Vascular and Endocrine Surgery, Agatharied Hospital, Hausham, Germany.
  • Zimmermann P; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
  • Kühn F; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
  • Werner J; Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, Marchioninistr. 15, D-81377, Munich, Germany.
  • Schardey HM; Department of General, Visceral, Vascular and Endocrine Surgery, Agatharied Hospital, Hausham, Germany.
  • Rau BM; Department of Surgery, Kliniken des Landkreises Neumarkt, Neumarkt, Germany.
  • Gumpp J; Department of Surgery, Kliniken des Landkreises Neumarkt, Neumarkt, Germany.
Int J Colorectal Dis ; 36(8): 1667-1676, 2021 Aug.
Article en En | MEDLINE | ID: mdl-33606074
PURPOSE: There is an ongoing debate on whether or not to use oral antibiotic bowel decontamination in colorectal surgery, despite the numerous different regimens in terms of antibiotic substances and duration of application. As we routinely use oral antibiotic bowel decontamination (selective decontamination of the digestive tract (SDD) regimen and SDD regimen plus vancomycin since 2016) in surgery for diverticular disease, our aim was to retrospectively analyze the perioperative outcome in two independent centers. METHODS: Data from two centers with a routine use of oral antibiotic bowel decontamination for up to 20 years of experience were analyzed for the perioperative outcome of 384 patients undergoing surgery for diverticular disease. RESULTS: Overall morbidity was 12.8%, overall mortality was 0.3%, the overall rate of anastomotic leakage (AL) was 1.0%, and surgical site infections (SSIs) were 5.5% and 7.8% of all infectious complications including urinary tract infections and pneumonia. No serious adverse events were related to use of oral antibiotic bowel decontamination. Most of the patients (93.8%) completed the perioperative regimen. Additional use of vancomycin to the SDD regimen did not show a further reduction of infectious complications, including SSI and AL. CONCLUSION: Oral antibiotic decontamination appears to be safe and effective with low rates of AL and infectious complications in surgery for diverticular disease.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Laparoscopía / Enfermedades Diverticulares Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: Int J Colorectal Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Laparoscopía / Enfermedades Diverticulares Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: Int J Colorectal Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania