A factor in human seminal plasma which affects carnitine accumulation in bovine epididymal sperm.
Fertil Steril
; 49(5): 893-9, 1988 May.
Article
en En
| MEDLINE
| ID: mdl-3360180
This study was initiated to determine whether factors are present in human sperm-free seminal plasma (HSP) that regulate the uptake and release of carnitine from sperm. Bovine caput epididymal sperm cells accumulated more carnitine than caudal sperm cells. A significant reduction in carnitine uptake by caput sperm was observed in the presence of HSP from normal subjects, but not from three subjects with reduced motility. A factor has been isolated from HSP that inhibits carnitine uptake by caput sperm and has the following properties: it is nondialyzable, stable to freeze-thawing, soluble in 60% ammonium sulfate, and has an approximate molecular weight of 158 kd. These data are consistent with the existence of a relatively high molecular weight protein in HSP responsible for the preservation of carnitine concentrations in sperm.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Semen
/
Espermatozoides
/
Carnitina
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Fertil Steril
Año:
1988
Tipo del documento:
Article
Pais de publicación:
Estados Unidos