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Highly Selective Y4 Receptor Antagonist Binds in an Allosteric Binding Pocket.
Schüß, Corinna; Vu, Oanh; Schubert, Mario; Du, Yu; Mishra, Nigam M; Tough, Iain R; Stichel, Jan; Weaver, C David; Emmitte, Kyle A; Cox, Helen M; Meiler, Jens; Beck-Sickinger, Annette G.
Afiliación
  • Schüß C; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany.
  • Vu O; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
  • Schubert M; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany.
  • Du Y; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Mishra NM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States.
  • Tough IR; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London SE1 1UL, U.K.
  • Stichel J; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany.
  • Weaver CD; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
  • Emmitte KA; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Cox HM; Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Meiler J; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States.
  • Beck-Sickinger AG; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London SE1 1UL, U.K.
J Med Chem ; 64(5): 2801-2814, 2021 03 11.
Article en En | MEDLINE | ID: mdl-33595306
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfonamidas / Receptores de Neuropéptido Y / Benzotiazoles Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfonamidas / Receptores de Neuropéptido Y / Benzotiazoles Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos