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Oligodendroglial glycolipids in (Re)myelination: implications for multiple sclerosis research.
Nowack, Luise; Teschers, Charlotte S; Albrecht, Stefanie; Gilmour, Ryan.
Afiliación
  • Nowack L; Institute for Organic Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstraße 36, 48149 Münster, Germany. ryan.gilmour@uni-muenster.de and Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149 Münster, Germany. stefanie.albrecht@ukmuenster.de.
  • Teschers CS; Institute for Organic Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstraße 36, 48149 Münster, Germany. ryan.gilmour@uni-muenster.de.
  • Albrecht S; Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149 Münster, Germany. stefanie.albrecht@ukmuenster.de.
  • Gilmour R; Institute for Organic Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstraße 36, 48149 Münster, Germany. ryan.gilmour@uni-muenster.de.
Nat Prod Rep ; 38(5): 890-904, 2021 05 26.
Article en En | MEDLINE | ID: mdl-33575689
Covering: up to 2020 This short review surveys aspects of glycolipid-based natural products and their biological relevance in multiple sclerosis (MS). The role of isolated gangliosides in disease models is discussed together with an overview of ganglioside-inspired small molecule drugs and imaging probes. The discussion is extended to neurodegeneration in a more general context and addresses the need for more efficient synthetic methods to generate (glyco)structures that are of therapeutic relevance.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucolípidos / Oligodendroglía / Gangliósidos / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Nat Prod Rep Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucolípidos / Oligodendroglía / Gangliósidos / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Nat Prod Rep Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido