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The seasonal pattern of restless legs syndrome in a sample from the Korean Health Insurance Review and Assessment Service national database.
Oh, Seong Min; Son, Kyung-Lak; Choi, Seok-Jin; Lee, Mi Hyun; Yoon, So Young; Lee, Yu Jin.
Afiliación
  • Oh SM; Department of Psychiatry, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
  • Son KL; Department of Psychiatry, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
  • Choi SJ; Department of Neurology, Inha University School of Medicine, Incheon, Republic of Korea.
  • Lee MH; Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
  • Yoon SY; Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
  • Lee YJ; Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
J Clin Sleep Med ; 17(5): 1051-1056, 2021 05 01.
Article en En | MEDLINE | ID: mdl-33570488
STUDY OBJECTIVES: To assess the seasonality of restless legs syndrome (RLS) using data from the Korean national health insurance database. METHODS: We retrospectively reviewed a randomly selected sample representing 3% of the national health insurance claims database in South Korea. From this sample, we obtained the monthly numbers of patients with RLS and diagnoses from 2009 to 2016, along with prescriptions for monthly dopamine agonists and clonazepam for patients with RLS from 2009 to 2013. Total dopamine agonist and clonazepam doses were converted to levodopa-equivalent doses, and the monthly cumulative prescription dose was calculated. Cosinor analysis was used to evaluate the seasonal pattern of each variable. RESULTS: This study included 11,466 patients with RLS and their diagnoses and 4,887 prescriptions for dopamine agonists and clonazepam. There were significant seasonal patterns in the numbers of patients with RLS (P < .001) and diagnoses (P < .001), both of which peaked in August. The magnitude of the greatest difference in the number of patients with RLS between August (highest) and February (lowest) was 29.96% (95% confidence interval, 24.03-100.80), and that of the number of RLS diagnoses was 39.56% (95% confidence interval, 31.24-47.89). The cumulative prescription dose of medication showed no significant seasonality. CONCLUSIONS: Our findings suggest that the prevalence of RLS is seasonally affected, with an increase during summer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de las Piernas Inquietas Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Clin Sleep Med Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de las Piernas Inquietas Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: J Clin Sleep Med Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos