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Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.
Chan, Ying Kai; Wang, Sean K; Chu, Colin J; Copland, David A; Letizia, Alexander J; Costa Verdera, Helena; Chiang, Jessica J; Sethi, Meher; Wang, May K; Neidermyer, William J; Chan, Yingleong; Lim, Elaine T; Graveline, Amanda R; Sanchez, Melinda; Boyd, Ryan F; Vihtelic, Thomas S; Inciong, Rolando Gian Carlo O; Slain, Jared M; Alphonse, Priscilla J; Xue, Yunlu; Robinson-McCarthy, Lindsey R; Tam, Jenny M; Jabbar, Maha H; Sahu, Bhubanananda; Adeniran, Janelle F; Muhuri, Manish; Tai, Phillip W L; Xie, Jun; Krause, Tyler B; Vernet, Andyna; Pezone, Matthew; Xiao, Ru; Liu, Tina; Wang, Wei; Kaplan, Henry J; Gao, Guangping; Dick, Andrew D; Mingozzi, Federico; McCall, Maureen A; Cepko, Constance L; Church, George M.
Afiliación
  • Chan YK; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. gchurch@genetics.med.harvard.edu yingkai_chan@hms.harvard.edu.
  • Wang SK; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Chu CJ; Ally Therapeutics, Cambridge, MA 02139, USA.
  • Copland DA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Letizia AJ; Academic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol BS8 1TD, UK.
  • Costa Verdera H; Academic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol BS8 1TD, UK.
  • Chiang JJ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Sethi M; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Wang MK; Inserm U974, Sorbonne Universite, Paris 75651, France.
  • Neidermyer WJ; Inserm S951 and Genethon, Evry 91000, France.
  • Chan Y; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Lim ET; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Graveline AR; Ally Therapeutics, Cambridge, MA 02139, USA.
  • Sanchez M; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Boyd RF; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Vihtelic TS; Ally Therapeutics, Cambridge, MA 02139, USA.
  • Inciong RGCO; Ally Therapeutics, Cambridge, MA 02139, USA.
  • Slain JM; Ally Therapeutics, Cambridge, MA 02139, USA.
  • Alphonse PJ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Xue Y; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Robinson-McCarthy LR; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Tam JM; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Jabbar MH; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Sahu B; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Adeniran JF; Ophthalmology, Charles River Laboratories, Mattawan, MI 49071, USA.
  • Muhuri M; Ophthalmology, Charles River Laboratories, Mattawan, MI 49071, USA.
  • Tai PWL; Statistics and Data Science, Charles River Laboratories, Mattawan, MI 49071, USA.
  • Xie J; Statistics and Data Science, Charles River Laboratories, Mattawan, MI 49071, USA.
  • Krause TB; Inserm U974, Sorbonne Universite, Paris 75651, France.
  • Vernet A; Inserm S951 and Genethon, Evry 91000, France.
  • Pezone M; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Xiao R; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Liu T; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Wang W; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Kaplan HJ; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Gao G; Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY 40202, USA.
  • Dick AD; Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY 40202, USA.
  • Mingozzi F; Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY 40202, USA.
  • McCall MA; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Cepko CL; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Church GM; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Sci Transl Med ; 13(580)2021 02 10.
Article en En | MEDLINE | ID: mdl-33568518
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dependovirus / Vectores Genéticos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dependovirus / Vectores Genéticos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos