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Retinoblastoma in an older Hispanic child masquerading as pars planitis: A case report.
Domínguez-Varela, Irving Armando; Aguilera-Partida, Jorge A; Dalvin, Lauren A; Garza-Garza, Lucas A; Thompson-García, Leslie M; Barbosa-Quintana, Álvaro; Ancona-Lezama, David.
Afiliación
  • Domínguez-Varela IA; Ocular Oncology Service, Institute of Ophthalmology and Visual Sciences, Tecnologico de Monterrey, Monterrey, Mexico.
  • Aguilera-Partida JA; Ophthalmological Clinic, Santa Lucía, Guadalajara, Jalisco, Mexico.
  • Dalvin LA; Department of Ophthalmology, Mayo Clinic, Rochester, MO, USA.
  • Garza-Garza LA; Ocular Oncology Service, Institute of Ophthalmology and Visual Sciences, Tecnologico de Monterrey, Monterrey, Mexico.
  • Thompson-García LM; University of the West of England, Bristol, England.
  • Barbosa-Quintana Á; Pathology Service, San Jose Hospital, Tecnologico de Monterrey, Mexico.
  • Ancona-Lezama D; Ocular Oncology Service, Institute of Ophthalmology and Visual Sciences, Tecnologico de Monterrey, Monterrey, Mexico.
Eur J Ophthalmol ; 32(3): NP71-NP74, 2022 May.
Article en En | MEDLINE | ID: mdl-33567900
INTRODUCTION: To report a case of a Hispanic girl with late-onset Retinoblastoma (Rb) who was misdiagnosed as a pars planitis prior to referral. Nearly 95% of all Rb cases are detected before age 5, and this patient was 8 years-old. METHODS: Case report of a late-onset Retinoblastoma with anterior chamber (AC) involvement plus the presence of an Ahmed valve. The patient had a history of a couple of months of topical therapy comprising medication for glaucoma, systemic steroids, and a filtration surgery (Ahmed valve), after that a biopsy was performed prior to referral. Upon arrival at our clinic, we performed an examination under anesthesia (EUA) and a B-scan ultrasound (US). RESULTS: Unilateral Retinoblastoma with an Ahmed valve in an AC filled with Rb seeds was diagnosed with the EUA and US in the left eye. An orbital exenteration with map biopsies of the left orbital cavity was performed with confirmation by histopathology of a poorly differentiated endophytic retinoblastoma with Bruch's membrane invasion. Follow-up sessions were then arranged as well as subsequent systemic chemotherapy cycles. CONCLUSION: Given the rare incidence of retinoblastoma in children older than 5 years old, it can be easily mistaken for other differential diagnoses and treated with filtration surgeries that could put the patient's life at risk. In this report, late-onset Rb diagnosis is highlighted as a differential diagnosis in children and adults with atypical uveitis, which required a multidisciplinary approach.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retinoblastoma / Pars Planitis / Uveítis Intermedia / Neoplasias de la Retina Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: México Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retinoblastoma / Pars Planitis / Uveítis Intermedia / Neoplasias de la Retina Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: México Pais de publicación: Estados Unidos