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Human cornea conservation in coconut water solution.
Cid, David Antonio Camelo; Araújo, Marília Cavalcante; Passos, Márcia Vitorino Sampaio; Brasil, Ivelise Regina Canito; Nunes, José Ferreira; Salgueiro, Cristiane Clemente de Melo; Nogueira, Sávio Carvalho; Costa, Dácio Carvalho.
Afiliación
  • Cid DAC; Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.
  • Araújo MC; Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.
  • Passos MVS; Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.
  • Brasil IRC; Faculdade de Medicina, Universidade Estadual do Ceará, Fortaleza, CE, Brazil.
  • Nunes JF; ACP Biotecnologia, Renorbio, Universidade Estadual do Ceará, Fortaleza, CE, Brazil.
  • Salgueiro CCM; ACP Biotecnologia, Renorbio, Universidade Estadual do Ceará, Fortaleza, CE, Brazil.
  • Nogueira SC; Universidade Estadual do Ceará, Fortaleza, CE, Brazil.
  • Costa DC; Faculdade de Medicina, Universidade Estadual do Ceará, Fortaleza, CE, Brazil.
Arq Bras Oftalmol ; 84(2): 163-169, 2021.
Article en En | MEDLINE | ID: mdl-33567016
PURPOSE: The aim of this study was to evaluate the physical and chemical characteristics of coconut water and to analyze the use of coconut water solution for the conservation of human corneas. METHODS: This was an experimental and controlled study performed at the Eye Bank of the General Hospital of Fortaleza. The coconut water-based solution was prepared at the Goat Seed Technology Laboratory of the Department of Veterinary Medicine of the State University of Ceará. Discarded corneas from the Eye Bank were divided into two groups for sequential experiments: G1, coconut water-based solution (experimental group), and G2, conservative treatment with OPTISOL GS® (control group). The osmolality of corneas in G1 was analyzed sequentially at 275, 300, 325, 345, 365, and 400 mOsm/L. The viability of the corneas was determined by specular microscopy and biomicroscopy on the first, third, and seventh days. RESULTS: Corneas preserved in a solution of 365 and 345 mOsm/L had a transparency of 8 mm until the third day and had diffuse edema in the periphery, central folds, and partial epithelium loss until the seventh day. The 365-mOsm/L solution was associated with the worst results during follow-up. Corneas placed in Optisol-GS retained their original aspects. CONCLUSIONS: Coconut water-based preservative partially maintained corneal transparency and epithelial integrity, especially during the first three days of follow-up. The coconut water-based solutions used were not effective for use as preservatives in a human eye bank.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preservación de Órganos / Cocos Límite: Humans Idioma: En Revista: Arq Bras Oftalmol Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preservación de Órganos / Cocos Límite: Humans Idioma: En Revista: Arq Bras Oftalmol Año: 2021 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil