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Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients.
Davar, Diwakar; Dzutsev, Amiran K; McCulloch, John A; Rodrigues, Richard R; Chauvin, Joe-Marc; Morrison, Robert M; Deblasio, Richelle N; Menna, Carmine; Ding, Quanquan; Pagliano, Ornella; Zidi, Bochra; Zhang, Shuowen; Badger, Jonathan H; Vetizou, Marie; Cole, Alicia M; Fernandes, Miriam R; Prescott, Stephanie; Costa, Raquel G F; Balaji, Ascharya K; Morgun, Andrey; Vujkovic-Cvijin, Ivan; Wang, Hong; Borhani, Amir A; Schwartz, Marc B; Dubner, Howard M; Ernst, Scarlett J; Rose, Amy; Najjar, Yana G; Belkaid, Yasmine; Kirkwood, John M; Trinchieri, Giorgio; Zarour, Hassane M.
Afiliación
  • Davar D; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Dzutsev AK; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • McCulloch JA; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Rodrigues RR; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Chauvin JM; Genetics and Microbiome Core, Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
  • Morrison RM; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Deblasio RN; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Menna C; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Ding Q; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Pagliano O; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Zidi B; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Zhang S; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Badger JH; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Vetizou M; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Cole AM; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Fernandes MR; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Prescott S; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Costa RGF; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Balaji AK; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Morgun A; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.
  • Vujkovic-Cvijin I; College of Pharmacy, Oregon State University, Corvallis, OR 97331, USA.
  • Wang H; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.
  • Borhani AA; Biostatistics Facility, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Schwartz MB; Division of Abdominal Imaging, Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Dubner HM; Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Ernst SJ; Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Rose A; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Najjar YG; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Belkaid Y; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Kirkwood JM; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.
  • Trinchieri G; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Zarour HM; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. zarourhm@upmc.edu trinchig@mail.nih.gov.
Science ; 371(6529): 595-602, 2021 02 05.
Article en En | MEDLINE | ID: mdl-33542131
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Resistencia a Antineoplásicos / Anticuerpos Monoclonales Humanizados / Receptor de Muerte Celular Programada 1 / Trasplante de Microbiota Fecal / Antineoplásicos Inmunológicos / Melanoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Science Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Resistencia a Antineoplásicos / Anticuerpos Monoclonales Humanizados / Receptor de Muerte Celular Programada 1 / Trasplante de Microbiota Fecal / Antineoplásicos Inmunológicos / Melanoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Science Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos