Gender Difference is Associated with Short-Term Outcomes in Non-Surgically Managed Acute Aortic Dissection Patients with Hypertension: A Retrospective Cohort Study.

Zhou, Yang; Peng, Wen; Yang, Guifang; Pan, Xiaogao; Ding, Ning; Zhang, Hongliang; Peng, Zhenyu; Zhang, Dongshan; Wu, Sijie; Chai, Xiangping

Zhou, Yang; Peng, Wen; Yang, Guifang; Pan, Xiaogao; Ding, Ning; Zhang, Hongliang; Peng, Zhenyu; Zhang, Dongshan; Wu, Sijie; Chai, Xiangping.

Afiliación

Zhou Y; Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Peng W; Emergency Medicine and Difficult Diseases Institute, Central South University, Changsha, People's Republic of China.
Yang G; Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Pan X; Emergency Medicine and Difficult Diseases Institute, Central South University, Changsha, People's Republic of China.
Ding N; Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Zhang H; Emergency Medicine and Difficult Diseases Institute, Central South University, Changsha, People's Republic of China.
Peng Z; Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Zhang D; Emergency Medicine and Difficult Diseases Institute, Central South University, Changsha, People's Republic of China.
Wu S; Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Chai X; Emergency Medicine and Difficult Diseases Institute, Central South University, Changsha, People's Republic of China.

Risk Manag Healthc Policy ; 14: 323-330, 2021.

Article en En | MEDLINE | ID: mdl-33536801

RESUMEN

BACKGROUND: The management of acute aortic dissection (AAD) has improved; however, the outcomes related to different gender with short-term outcomes in non-surgically managed AAD with hypertension are still limited. Our objective was to explore gender-differences in association with short-term outcomes of patients comorbid with hypertension in non-surgically managed AAD. METHODS: This is an observational retrospective single-center cohort. We analyzed the data from the Second Xiangya Hospital of Central South University (2014-2018). The data on demographics, clinical presentation, chronic comorbidities, laboratory testing, imaging studies, and treatment were analyzed for all patients. Univariate and multiple analyses were used to test gender-difference associated with short-term outcomes of patients with hypertension in non-surgically managed AAD. RESULTS: In total, 288 patients were enrolled in this study, of whom 238 (82.63%) were male and 50 (17.37%) were females. About 74% of female patients were dead in-hospital, which was more than male patients (56.3%). Female patients with diabetes mellitus were more than male patients (14% vs 2.94%), while male patients with smoking were significant higher than female patients (36.55% vs 8%). In the full model (model 3), after adjusting for confounding variables, the female AAD patients were more likely to have worse short-term outcomes (OR=3.60, 95% CI=1.41 to 9.60). CONCLUSION: Female patients were more likely to have worse outcomes in non-surgically managed AAD patients with hypertension. Large numbers of investigations are required to further explore this relationship.

Palabras clave

aortic dissection; gender-differences; hypertension; short-term outcomes

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Idioma: En Revista: Risk Manag Healthc Policy Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google