Chromosomal damage induced by maleic hydrazide in mammalian cells in vitro and in vivo.
Mutat Res
; 204(4): 645-8, 1988 Apr.
Article
en En
| MEDLINE
| ID: mdl-3352645
The induction of sister-chromatid exchanges (SCE) and chromosomal aberrations (Ch.Ab.) by the herbicide maleic hydrazide (MH) has been investigated in Chinese hamster ovary (CHO) cells grown in vitro and in bone marrow cells of mice treated in vivo. MH induces SCE and Ch.Ab. in CHO cells without metabolic activation; however, no induction of SCE was found in the in vivo experiments.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piridazinas
/
Cromosomas
/
Hidrazida Maleica
Límite:
Animals
Idioma:
En
Revista:
Mutat Res
Año:
1988
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Países Bajos