Effective Activation by Kynurenic Acid and Its Aminoalkylated Derivatives on M-Type K<sup>+</sup> Current.

Lo, Yi-Ching; Lin, Chih-Lung; Fang, Wei-Yu; Lorinczi, Bálint; Szatmári, István; Chang, Wan-Hsuan; Fülöp, Ferenc; Wu, Sheng-Nan

Effective Activation by Kynurenic Acid and Its Aminoalkylated Derivatives on M-Type K⁺ Current.

Lo, Yi-Ching; Lin, Chih-Lung; Fang, Wei-Yu; Lorinczi, Bálint; Szatmári, István; Chang, Wan-Hsuan; Fülöp, Ferenc; Wu, Sheng-Nan.

Afiliación

Lo YC; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Lin CL; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Fang WY; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Lorinczi B; Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Szatmári I; Department of Neurosurgery, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chang WH; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Fülöp F; Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Wu SN; Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.

Int J Mol Sci ; 22(3)2021 Jan 28.

Article en En | MEDLINE | ID: mdl-33525680

Asunto(s)

Hipocampo/fisiología; Canales de Potasio KCNQ/efectos de los fármacos; Ácido Quinurénico/farmacología; Animales; Apamina/farmacología; Línea Celular; Hipocampo/efectos de los fármacos; Hipocampo/metabolismo; Indoles/farmacología; Ácido Quinurénico/química; Potenciales de la Membrana/efectos de los fármacos; Ratones; Técnicas de Placa-Clamp; Péptidos/farmacología; Piridinas/farmacología; Ratas

Palabras clave

M-type K+ current; action potential; hippocampal neuron; kynurenic acid; kynurenic acid derivative; pituitary cell

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Canales de Potasio KCNQ / Hipocampo / Ácido Quinurénico Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza

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