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The Next Generation of Ocular Pathogen Detection.
Sabapathypillai, Sharon L; James, Hayley R; Lyerla, Rachael R L; Hassman, Lynn.
Afiliación
  • Sabapathypillai SL; Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, MO.
Asia Pac J Ophthalmol (Phila) ; 10(1): 109-113, 2021.
Article en En | MEDLINE | ID: mdl-33512832
ABSTRACT: Metagenomic next-generation sequencing is a powerful method for pathogen detection that combines advanced genome sequencing technology with cutting-edge bioinformatics to analyze microbial populations. Metagenomic next-generation sequencing has the potential to identify uncommon, unculturable, and even previously unidentified pathogens from a clinical isolate. Of particular interest to ophthalmology, this robust data extraction can occur from very small volume clinical samples. Here we discuss the opportunities and limitations of this technique and their current and future application to ophthalmic diagnostics.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oftalmopatías / Metagenoma / Metagenómica Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Asia Pac J Ophthalmol (Phila) Año: 2021 Tipo del documento: Article Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oftalmopatías / Metagenoma / Metagenómica Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Asia Pac J Ophthalmol (Phila) Año: 2021 Tipo del documento: Article Pais de publicación: China