Design of turn-on luminescent sensor based on nanostructured molecularly imprinted polymer-coated zirconium metal-organic framework for selective detection of chloramphenicol residues in milk and honey.
Food Chem
; 347: 129034, 2021 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-33486363
Herein, an optical sensor based on nanostructured molecularly imprinted polymer (MIP) coated on a luminescent zirconium metal-organic framework (MIP/Zr-LMOF) is introduced, and its performance is investigated for the fluorescent determination of chloramphenicol (CAP) antibiotic residues in milk and honey. To fabricate the sensor, the surface of Zr-LMOF is modified with MIP in the presence of CAP template, resulting in the introduction of recognition sites for antibiotic molecules. The porous structure of Zr-LMOF with specific binding sites for CAP recognition benefiting from coated MIP leads to selective and sensitive detection of antibiotic. The probe yields a linear range for detection of CAP in trace concentrations (0.16-161.56 µg.L-1) and provides a detection limit of 0.013 µg.L-1. Acceptable recoveries are achieved for antibiotic in real samples, which are consistent with that obtained from liquid chromatography-tandem mass spectrometry (LC-MS/MS), confirm the favorable performance of sensor for accurate determination of CAP in practical applications.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Circonio
/
Cloranfenicol
/
Leche
/
Nanoestructuras
/
Estructuras Metalorgánicas
/
Polímeros Impresos Molecularmente
/
Miel
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Food Chem
Año:
2021
Tipo del documento:
Article
País de afiliación:
Irán
Pais de publicación:
Reino Unido