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Lyophilization stabilizes clinical-stage core-crosslinked polymeric micelles to overcome cold chain supply challenges.
Ojha, Tarun; Hu, Qizhi; Colombo, Claudio; Wit, Jan; van Geijn, Michiel; van Steenbergen, Mies J; Bagheri, Mahsa; Königs-Werner, Hiltrud; Buhl, Eva Miriam; Bansal, Ruchi; Shi, Yang; Hennink, Wim E; Storm, Gert; Rijcken, Cristianne J F; Lammers, Twan.
Afiliación
  • Ojha T; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Hu Q; Department of Pharmaceutics, Utrecht University, Utrecht, The Netherlands.
  • Colombo C; Department of Medical Cell BioPhysics, Faculty of Science and Technology, University of Twente, Translational Liver Research, Enschede, The Netherlands.
  • Wit J; Cristal Therapeutics, Maastricht, The Netherlands.
  • van Geijn M; Cristal Therapeutics, Maastricht, The Netherlands.
  • van Steenbergen MJ; Saudade Pharma Consultancy, Eijsden, The Netherlands.
  • Bagheri M; Cristal Therapeutics, Maastricht, The Netherlands.
  • Königs-Werner H; Department of Pharmaceutics, Utrecht University, Utrecht, The Netherlands.
  • Buhl EM; Department of Pharmaceutics, Utrecht University, Utrecht, The Netherlands.
  • Bansal R; Electron Microscope Facility, University Hospital RWTH, RWTH Aachen University, Aachen, Germany.
  • Shi Y; Electron Microscope Facility, University Hospital RWTH, RWTH Aachen University, Aachen, Germany.
  • Hennink WE; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Storm G; Department of Medical Cell BioPhysics, Faculty of Science and Technology, University of Twente, Translational Liver Research, Enschede, The Netherlands.
  • Rijcken CJF; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Lammers T; Department of Pharmaceutics, Utrecht University, Utrecht, The Netherlands.
Biotechnol J ; 16(6): e2000212, 2021 Jun.
Article en En | MEDLINE | ID: mdl-33484630
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Refrigeración / Micelas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biotechnol J Asunto de la revista: BIOTECNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Refrigeración / Micelas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biotechnol J Asunto de la revista: BIOTECNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania