Your browser doesn't support javascript.
loading
Cardiac troponin release following left bundle branch pacing.
Ponnusamy, Shunumuga S; Patel, Neil R; Naperkowski, Angela; Subzposh, Faiz A; Vijayaraman, Pugazhendhi.
Afiliación
  • Ponnusamy SS; Division of Cardiology, Velammal Medical College, Madurai, Tamil Nadu, India.
  • Patel NR; Division of Cardiology, The Wright Center, Scranton, Pennsylvania, USA.
  • Naperkowski A; Division of Cardiology, Geisinger Heart Institute, Wilkes-Barre, Pennsylvania, USA.
  • Subzposh FA; Division of Cardiology, Geisinger Heart Institute, Wilkes-Barre, Pennsylvania, USA.
  • Vijayaraman P; Division of Cardiology, Geisinger Heart Institute, Wilkes-Barre, Pennsylvania, USA.
J Cardiovasc Electrophysiol ; 32(3): 851-855, 2021 03.
Article en En | MEDLINE | ID: mdl-33484212
Left bundle branch pacing (LBBP) has emerged as an alternative to His bundle pacing (HBP) to achieve physiologic ventricular stimulation. The extent of myocardial injury during permanent LBBP implantation is currently not known. The aim of the study was to prospectively assess the extent of myocardial injury during LBBP implantation. Cardiac troponin (cTn) levels were measured at baseline and 6-12 h following permanent LBBP. The number of attempts to achieve LBBP was documented. Troponin levels were measured in a control population undergoing other electrophysiology procedures including HBP, other devices involving right ventricular (RV) pacing, radiofrequency ablation for atrial fibrillation (AF) and supraventricular tachycardia (SVT). Significant elevation of troponin (SET) was defined as threefold increase above the upper reference limit (URL) for cTn. Between December 2019 and April 2020, 204 were prospectively enrolled: LBBP in 98 and Control group 106 (SVT, 55; AF, 20; HBP, 17; other devices, 14). SET (>3× URL) was seen in 49.4% of patients in the LBBP group compared to 58.4% in the control group (p = .23). Peak troponin levels were greater in the control group compared to the LBBP group (230.3 ± 320.1 vs. 87.4 ± 71.3 pg/ml; p = .0001). Compared to LBBP (49.4%), SET was observed less frequently following HBP (17.5%; p = .01), and other device implantation (29%; p = .15). Patients requiring >2 attempts (n = 33) had significantly higher incidence of SET compared to <2 attempts (n = 56; 66.7% vs. 39.3%; p = .01). LBBP implantation is associated with myocardial injury. Asymptomatic troponin release following LBBP is less than or comparable to other interventional electrophysiology procedures.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fascículo Atrioventricular / Estimulación Cardíaca Artificial Límite: Humans Idioma: En Revista: J Cardiovasc Electrophysiol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fascículo Atrioventricular / Estimulación Cardíaca Artificial Límite: Humans Idioma: En Revista: J Cardiovasc Electrophysiol Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos